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Displaying results 4171 - 4180 of 10000 in total
  1. Target

    P2X purinoceptor 4

    go.drugbank.com/bio_entities/BE0005793
    TargetHumans

    ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:9016352). CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4 (By similarity). Activated by extracellularly releas...

    Polypeptides: P2X purinoceptor 4
  2. Target

    Melanocortin receptor 4

    go.drugbank.com/bio_entities/BE0009682
    TargetHumans

    G protein-coupled receptor that binds melanocyte-stimulating hormones (alpha- and beta-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:12646665, PubMed:14764818, PubMed:25163632, PubMed:32327598, Pub...

    Polypeptides: Melanocortin receptor 4
  3. Target

    Platelet glycoprotein 4

    go.drugbank.com/bio_entities/BE0010538
    TargetTransporterHumans

    Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-densit...

    Polypeptides: Platelet glycoprotein 4Synonyms: PAS-4
  4. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. … Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.

    Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
  5. Target

    Monocarboxylate transporter 4

    go.drugbank.com/bio_entities/BE0000449
    TargetTransporterHumans

    Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate (PubMed:11101640, PubMed:23935841, PubMed:31719150). Plays a predominant role in L-lactate efflux from highly glycolytic cells (By similarity)

    Polypeptides: Monocarboxylate transporter 4Synonyms: MCT 4
  6. Target

    Carbonic anhydrase 4

    go.drugbank.com/bio_entities/BE0000535
    TargetEnzymeHumans

    Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH (PubMed:15563508, PubMed:16686544, PubMed:16807956, PubMed:17127057, PubMed:1731404...

    Polypeptides: Carbonic anhydrase 4
  7. Target

    Phenylalanine-4-hydroxylase

    go.drugbank.com/bio_entities/BE0000753
    TargetEnzymeHumans

    Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine

    Polypeptides: Phenylalanine-4-hydroxylaseSynonyms: Phe-4-monooxygenase
  8. Target

    Glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000830
    TargetHumans

    Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 4Synonyms: GluR-4, AMPA-selective glutamate receptor 4
  9. Target

    4-alpha-glucanotransferase

    go.drugbank.com/bio_entities/BE0001664
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: 4-alpha-glucanotransferaseFunction: 4-alpha-glucanotransferase activity
  10. Target

    Endoglucanase E-4

    go.drugbank.com/bio_entities/BE0003251
    TargetThermomonospora fusca

    Polypeptides: Endoglucanase E-4Synonyms: Cellulase E-4, Endo-1,4-beta-glucanase E-4