Search
Vilazodone
go.drugbank.com/drugs/DB06684ApprovedInvestigationalVilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622].
Categories: Membrane Transport ModulatorsUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalUbidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid...
Mixtures: Complex, ComplexCategories: Electron Transport Chain Complex ProteinsLarge neutral amino acids transporter small subunit 1
go.drugbank.com/bio_entities/BE0000222TransporterTargetHumansForms a heterodimer with SLC3A2 that functions as a sodium-independent transporter for large neutral amino acids (PubMed:9751058, PubMed:10049700, PubMed:11557028, PubMed:10574970, PubMed:11564694, PubMed … Involved in the cellular activity of low-molecular-weight nitrosothiols through stereoselective transport of L-nitrosocysteine (L-CNSO) across the plasma membrane (PubMed:15769744).
Polypeptides: Large neutral amino acids transporter small subunit 1Synonyms: L-type amino acid transporter 1, y+ system cationic amino acid transporterSolute carrier organic anion transporter family member 2B1
go.drugbank.com/bio_entities/BE0001042TransporterTargetHumansMay contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (Probable). … Also transports heme by-product coproporphyrin III (CPIII), and may be involved in their hepatic disposition (PubMed:26383540).
Polypeptides: Solute carrier organic anion transporter family member 2B1Synonyms: Organic anion transporter B, Organic anion transporter polypeptide-related protein 2Solute carrier organic anion transporter family member 1A2
go.drugbank.com/bio_entities/BE0003642TransporterHumansCapable of thyroid hormone transport (both T3 or 3,3',5'-triiodo-L-thyronine, and T4 or L-tyroxine) (PubMed:19129463, PubMed:20358049). Also transports prostaglandin E2 (PubMed:19129463). … May contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (Probable)
Polypeptides: Solute carrier organic anion transporter family member 1A2Synonyms: Sodium-independent organic anion transporterSolute carrier organic anion transporter family member 4C1
go.drugbank.com/bio_entities/BE0003653TransporterTargetHumansTransport activity is stimulated by an acidic extracellular environment due to increased substrate affinity to the transporter (PubMed:19129463). … Transport is independent of sodium, chloride ion, and ATP (PubMed:14993604).
Polypeptides: Solute carrier organic anion transporter family member 4C1Synonyms: Organic anion transporter M1Solute carrier organic anion transporter family member 2A1
go.drugbank.com/bio_entities/BE0003655TransporterHumansEssential core component of the major type of large-conductance anion channel, Maxi-Cl, which plays essential roles in inorganic anion transport, cell volume regulation and release of ATP and glutamate … When apically expressed in epithelial cells, it facilitates transcellular transport (also called vectorial release), extracting PG from the apical medium and facilitating transport across the cell toward
Polypeptides: Solute carrier organic anion transporter family member 2A1Synonyms: Prostaglandin transporterSolute carrier organic anion transporter family member 4A1
go.drugbank.com/bio_entities/BE0003656TransporterHumansThe transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable) … Possibly drives the selective transport of thyroid hormones and estrogens coupled to an outward glutamate gradient across the microvillous membrane of the placenta (PubMed:30343886).
Polypeptides: Solute carrier organic anion transporter family member 4A1Synonyms: Colon organic anion transporter, Sodium-independent organic anion transporter ESolute carrier organic anion transporter family member 1C1
go.drugbank.com/bio_entities/BE0003660TransporterHumansTransports T4 and E1S in a pH-insensitive manner (PubMed:19129463). … Facilitates the transport of thyroid hormones across the blood-brain barrier and into glia and neuronal cells in the brain (PubMed:30296914)
Polypeptides: Solute carrier organic anion transporter family member 1C1Synonyms: Thyroxine transporter, Organic anion transporter FSolute carrier organic anion transporter family member 3A1
go.drugbank.com/bio_entities/BE0003661TransporterHumansThe transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable). Mediates transport of tryptophan, phenyalanine and tyrosine (PubMed:39206635)
Polypeptides: Solute carrier organic anion transporter family member 3A1Synonyms: PGE1 transporter, Sodium-independent organic anion transporter D