Solute carrier organic anion transporter family member 2B1

BE0001042ProteinHumansSLCO2B1

Mediates the Na(+)-independent transport of steroid sulfate conjugates and other specific organic anions (PubMed:10873595, PubMed:11159893, PubMed:11932330, PubMed:12724351, PubMed:14610227, PubMed:16908597, PubMed:18501590, PubMed:20507927, PubMed:22201122, PubMed:23531488, PubMed:25132355, PubMed:26383540, PubMed:27576593, PubMed:28408210, PubMed:29871943, PubMed:34628357). It is acted on by 85 drugs in DrugBank.

Gene name
SLCO2B1
UniProtKB entry
O94956Swiss-Prot
Cellular location
Cell membrane
Residues / weight
709 residues · 76,698 Da
Also known as
KIAA0880 · OATP-B · OATP-RP2 · OATP2B1 · OATPB

Resolves to

Protein
UniProtO94956UniProt nameSO2B1_HUMAN
Gene
HGNCHGNC:10962NCBI Gene11309GenBank5006263GeneCardsSLCO2B1
Pharmacology
IUPHAR/GtoPdb1224KEGGhsa:11309
Drugs

What you can answer from here — as of September 07, 2019

85DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
9GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
114+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Solute carrier organic anion transporter family member 2B1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In