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Glucose-6-phosphate exchanger SLC37A4
go.drugbank.com/bio_entities/BE0011751TargetHumansInorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum (PubMed:10026167, PubMed:21949678). … Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction (PubMed:41136424, PubMed:41225049, PubMed:33964207
Polypeptides: Glucose-6-phosphate exchanger SLC37A4Synonyms: Solute carrier family 37 member 4, Glucose-6-phosphate translocasePutative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
go.drugbank.com/bio_entities/BE0001689TargetMycobacterium tuberculosisCatalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.
Polypeptides: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolaseFunction: 4-hydroxy-4-methyl-2-oxoglutarate aldolase activityDoxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigationalDoxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. … [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedioneAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalA high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases. … A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818].
Products: Simlandi 40 mg/0.4 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 6 ADET, Simlandi 40 mg/0.4 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 6 ADETIohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideMixtures: Dexlido M-C, Mlk F4-CBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalMoreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base. … Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties
Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 MLCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingChymopapain
go.drugbank.com/drugs/DB06752ApprovedWithdrawnChymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982.
Products: Chymodiactin Injection - 4 Nkat Units/2mlFosgemcitabine palabenamide
go.drugbank.com/drugs/DB15057InvestigationalNUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Categories: Heterocyclic Compounds, 1-RingSynonyms: BENZYL (2S)-2-((((2R,3R,5R)-5-(4-AMINO-2-OXO-PYRIMIDIN-1-YL)-4,4-DIFLUORO-3-HYDROXY-TETRAHYDROFURAN-2-YL)METHOXY-PHENOXY-PHOSPHORYL)AMINO)PROPANOATE, L-Alanine, N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-, phenylmethyl esterGlucose-6-phosphate 1-dehydrogenase
go.drugbank.com/bio_entities/BE0001439TargetLeuconostoc mesenteroidesCatalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone. Can utilize either NADP(+) or NAD(+).
Polypeptides: Glucose-6-phosphate 1-dehydrogenaseSynonyms: Glucose-6-phosphate dehydrogenase (NAD(P)(+))Glucosamine-6-phosphate deaminase 1
go.drugbank.com/bio_entities/BE0001567TargetHumansCatalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine
Polypeptides: Glucosamine-6-phosphate deaminase 1Synonyms: Glucosamine-6-phosphate isomerase 1