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Displaying results 4251 - 4260 of 10000 in total
  1. Target

    Carbonic anhydrase 4

    go.drugbank.com/bio_entities/BE0000535
    TargetEnzymeHumans

    Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH (PubMed:15563508, PubMed:16686544, PubMed:16807956, PubMed:17127057, PubMed:1731404...

    Polypeptides: Carbonic anhydrase 4
  2. Target

    Phenylalanine-4-hydroxylase

    go.drugbank.com/bio_entities/BE0000753
    TargetEnzymeHumans

    Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine

    Polypeptides: Phenylalanine-4-hydroxylaseSynonyms: Phe-4-monooxygenase
  3. Target

    Glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000830
    TargetHumans

    Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic … The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (By similarity).

    Polypeptides: Glutamate receptor 4Synonyms: GluR-4, AMPA-selective glutamate receptor 4
  4. Target

    4-alpha-glucanotransferase

    go.drugbank.com/bio_entities/BE0001664
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: 4-alpha-glucanotransferaseFunction: 4-alpha-glucanotransferase activity
  5. Target

    Endoglucanase E-4

    go.drugbank.com/bio_entities/BE0003251
    TargetThermomonospora fusca

    Polypeptides: Endoglucanase E-4Synonyms: Cellulase E-4, Endo-1,4-beta-glucanase E-4
  6. Target

    Aminoglycoside nucleotidyltransferase (4')

    go.drugbank.com/bio_entities/BE0003547
    EnzymeStaphylococcus aureus

    Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.

    Polypeptides: Aminoglycoside nucleotidyltransferase (4')Synonyms: ANT(4')
  7. Target

    Interferon alpha-4

    go.drugbank.com/bio_entities/BE0012570
    TargetHumans

    Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

    Polypeptides: Interferon alpha-4Synonyms: IFN-alpha-4
  8. Target

    NADPH oxidase 4

    go.drugbank.com/bio_entities/BE0019855
    TargetEnzymeHumans

    May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation (PubMed:16324151). … May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB (PubMed:15356101, PubMed:15572675).

    Polypeptides: NADPH oxidase 4
  9. Drug

    Gliclazide

    go.drugbank.com/drugs/DB01120
    ApprovedInvestigational

    [A39546] On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life. … a sulfonamide group able to release a proton and the presence of one aromatic group.

    Mixtures: DUODİA 80 MG/500 MG TABLET, 30 ADET, GLIFOR PLUS 30 MG/1000 MG DEĞIŞTIRILMIŞ SALIMLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  10. Target

    4-hydroxyphenylpyruvate dioxygenase

    go.drugbank.com/bio_entities/BE0000455
    TargetHumans

    In addition may act as a N6-methyltransferase that methylates adenosine residues at the N(6) position of some RNAs (PubMed:10942115) … Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism (PubMed:10942115, PubMed:1339442, PubMed:34047349, PubMed:37794595).

    Polypeptides: 4-hydroxyphenylpyruvate dioxygenaseSynonyms: 4-hydroxyphenylpyruvic acid oxidase