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Displaying results 4281 - 4290 of 10000 in total
  1. Target

    Chondroitin sulfate proteoglycan 4

    go.drugbank.com/bio_entities/BE0015621
    TargetHumans

    May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades

    Polypeptides: Chondroitin sulfate proteoglycan 4
  2. Target

    Lysyl oxidase homolog 4

    go.drugbank.com/bio_entities/BE0018464
    TargetHumans

    Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers

    Polypeptides: Lysyl oxidase homolog 4Synonyms: Lysyl oxidase-like protein 4
  3. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension. … It was developed from a targeted research programmed using molecular modelling.

    Mixtures: Renitec plus 20 mg/6 mg Tabletten, Enac plus Hexal 20 mg/6 mg - TablettenCategories: P-glycoprotein inhibitors
  4. Target

    Solute carrier family 12 member 6

    go.drugbank.com/bio_entities/BE0000140
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10600773, PubMed:11551954, PubMed:16048901, PubMed:18566107, PubMed:19665974, PubMed:21628467, PubMed:27485015). May contribute to cell volume...

    Polypeptides: Solute carrier family 12 member 6
  5. Target

    Solute carrier family 22 member 6

    go.drugbank.com/bio_entities/BE0001066
    TransporterTargetEnzymeHumans

    Uremic toxins include the indoxyl sulfate (IS), hippurate/N-benzoylglycine (HA), indole acetate (IA), 3-carboxy-4- methyl-5-propyl-2-furanpropionate (CMPF) and urate (PubMed:14675047, PubMed:26377792).

    Polypeptides: Solute carrier family 22 member 6
  6. Target

    Inactive protein-arginine deiminase type-6

    go.drugbank.com/bio_entities/BE0002313
    TargetHumans

    Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development (PubMed:37922900, PubMed:41772195). Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplant...

    Polypeptides: Inactive protein-arginine deiminase type-6Synonyms: Protein-arginine deiminase type-6
  7. Target

    Cytochrome b6-f complex subunit 6

    go.drugbank.com/bio_entities/BE0003907
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (PubMed:14526088). PetL is important for photoautotr...

    Polypeptides: Cytochrome b6-f complex subunit 6
  8. Target

    Cation-dependent mannose-6-phosphate receptor

    go.drugbank.com/bio_entities/BE0004494
    TargetTransporterHumans

    Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal

    Polypeptides: Cation-dependent mannose-6-phosphate receptorSynonyms: CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptor
  9. Target

    Serine/threonine-protein kinase PAK 6

    go.drugbank.com/bio_entities/BE0009509
    TargetHumans

    Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR a...

    Polypeptides: Serine/threonine-protein kinase PAK 6Synonyms: PAK-6, p21-activated kinase 6
  10. Target

    ATP-dependent 6-phosphofructokinase, muscle type

    go.drugbank.com/bio_entities/BE0012586
    TargetHumans

    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

    Polypeptides: ATP-dependent 6-phosphofructokinase, muscle typeSynonyms: 6-phosphofructokinase type A