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Amitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]
Synonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamineCategories: Analgesics, Non-Narcotic, Non-Selective Monoamine Reuptake InhibitorsAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure [A175321].
Synonyms: 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateMixtures: VARTERAL NF® 320 MG / 5 MG, VARTERAL NF® 320 MG / 5 MGSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalIt has an identical primary protein structure to endogenous human growth hormone.[A228188] Recombinant HGH has been commercially available since 1985 after its development by Genentech. … [Somatrem] was the first available recombinant HGH and was largely replaced by somatropin, another form of recombinant HGH.
Products: NORDITROPIN 4 UI, GROWTROPINAQ 16 U /2 ML INYECTABLEFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.
Products: NEUPOGEN 30 MIO U 0.3MG/ML VIAL, INMUNEF 30 UI SOLUCION INYECTABLEPadimate O
go.drugbank.com/drugs/DB11570ApprovedPadimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage.
Mixtures: Dermatone SPF 23 Lips N Face Protector, Alba Botanica UN-petroleum Vanilla SPF18 Lip BalmSynonyms: Padimate O, Padimate-OAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approved[A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum concentrations than ampicillin. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]
Mixtures: CO-AMOXICLAV, CO-AMOXICLAVProducts: NEO AMPIPLUS, NEO TETRANASECiclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Categories: Agents to Treat Airway DiseaseProducts: ALVESCO 160 UG 120 HUBGlioblastoma Multiforme (GBM)
go.drugbank.com/conditions/DBCOND0046976Drugs: NimotuzumabSynonyms: Glioblastoma, no ICD-O subtype, Glioblastoma, no International Classification of Diseases for Oncology subtypeZeatin
go.drugbank.com/drugs/DB11337InvestigationalAn aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)
Synonyms: (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol, N6-(4-Hydroxyisopentenyl)adenineCarcinoid Tumors
go.drugbank.com/conditions/DBCOND0030495Drugs: PentetreotideSynonyms: Carcinoid tumour no ICD-O subtype, Carcinoid tumor no ICD-O subtype