NCT05023551
Study of DSP-0390 in Patients with Recurrent High-Grade Glioma No drug interventions treatment 0 active_not_recruiting NCT05190315
Chlorpromazine and Standard of Care in Glioblastoma treatment 1 active_not_recruiting NCT05271240
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM treatment 3 recruiting NCT05303467
A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM No drug interventions treatment 0 recruiting NCT05423210
Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme treatment 0 recruiting NCT05839379
Targeted Pediatric High-Grade Glioma Therapy No drug interventions Not Available Not Available recruiting NCT05843253
Study of Ribociclib and Everolimus in HGG and DIPG treatment 2 recruiting NCT05954858
Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma No drug interventions treatment Not Available recruiting NCT05977322
A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors. treatment 1 recruiting NCT05979064
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) No drug interventions treatment Not Available recruiting NCT06059690
Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells No drug interventions diagnostic 1 / 2 recruiting NCT06404034
Expanded Access to Gallium Maltolate (GaM) Not Available Not Available available NCT00376103
Radiation Boost for Newly Diagnosed Glioblastoma Multiforme treatment 1 / 2 terminated NCT00107003
GW572016 to Treat Recurrent Malignant Brain Tumors treatment 2 completed NCT03291990
5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme other 0 completed NCT02654964
Cancer Stem Cell High-Throughput Drug Screening Study No drug interventions treatment 1 completed NCT03672721
IA Carboplatin + Radiotherapy in Relapsing GBM No drug interventions treatment 1 / 2 recruiting NCT05956821
Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age treatment 1 / 2 recruiting NCT05917821
New Antigens Against Glioblastoma No drug interventions Not Available Not Available not_yet_recruiting NCT06346821
Tumor Treating Fields for Newly Diagnosed Glioblastoma: Two Emulated Trials With Chinese Multi-Hospital Based Real-World Data No drug interventions Not Available Not Available completed NCT02507102
A Feasibility Study of the Nativis Voyager® System in Patients With Recurrent Glioblastoma Multiforme (GBM) in Australia No drug interventions treatment Not Available completed NCT00112502
Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme treatment 2 completed NCT03389802
Phase I Study of APX005M in Pediatric CNS Tumors treatment 1 active_not_recruiting NCT00817284
Bevacizumab and Irinotecan or Bevacizumab and Temozolomide With Concomitant Radiotherapy for Primary Glioblastoma Multiforme (GBM) treatment 2 completed NCT02022384
Immunophenotyping From Blood of Patients With Malignant Gliomas No drug interventions Not Available Not Available completed NCT05120284
Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM) treatment 2 recruiting NCT04478279
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors treatment 1 / 2 active_not_recruiting NCT03607643
A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies treatment 1 / 2 unknown_status NCT02120287
Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme treatment 2 completed NCT03673787
A Trial of Ipatasertib in Combination With Atezolizumab health_services_research 1 / 2 unknown_status NCT01856933
BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM) No drug interventions treatment 2 completed NCT05083754
Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma treatment 1 recruiting NCT01478854
Neural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide treatment Not Available completed NCT03705351
Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM treatment 1 terminated NCT01269853
Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA treatment 1 / 2 recruiting NCT01618747
An Observational Study of Avastin (Bevacizumab) in Patients With Glioblastoma Multiforme in First or Second Relapse No drug interventions Not Available Not Available completed NCT00083447
Study of Therapy With TransMID™ Compared to Best Standard of Care in Patients With Glioblastoma Multiforme treatment 3 withdrawn NCT03665545
Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma treatment 1 / 2 active_not_recruiting NCT01811498
Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM treatment 1 / 2 completed NCT01931098
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab treatment 2 completed NCT03347097
Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme No drug interventions treatment 0 unknown_status NCT01562197
A Randomized Phase II Clinical Trial on the Efficacy of Axitinib as a Monotherapy or in Combination With Lomustine for the Treatment of Patients With Recurrent Glioblastoma treatment 2 completed NCT01177397
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma treatment 1 / 2 completed NCT06356883
Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma treatment 2 recruiting NCT01124461
BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor No drug interventions Not Available Not Available completed NCT05589961
Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme No drug interventions treatment 0 recruiting NCT00430911
Radiotherapy for Malignant Astrocytomas in the Elderly No drug interventions treatment 3 completed NCT01181193
Vitamin D for Treatment of Glioblastoma Multiforme treatment 1 / 2 unknown_status NCT00613093
Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma treatment 2 completed NCT03712293
ExAblate Blood-Brain Barrier Disruption for Glioblastoma in Patients Undergoing Standard Chemotherapy No drug interventions treatment Not Available completed NCT03961971
Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM treatment 1 active_not_recruiting NCT06496971
A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients treatment 3 not_yet_recruiting NCT01478178
Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma treatment 1 / 2 completed NCT02939378
Ketogenic Diet Adjunctive to Salvage Chemotherapy for Recurrent Glioblastoma:a Pilot Study No drug interventions treatment 1 / 2 unknown_status NCT02177578
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme treatment 2 recruiting NCT03911388
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors treatment 1 active_not_recruiting NCT00704288
Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme treatment 2 completed NCT01317888
Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas No drug interventions treatment Not Available unknown_status NCT00004688
Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms treatment 2 completed NCT00179907
A Phase I/II Study of the Photon Radiosurgery System No drug interventions treatment 1 / 2 completed NCT02189109
The Effects of NVX-108 as a Radiation Sensitizer in Glioblastoma treatment 1 completed NCT02715609
Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma treatment 1 / 2 active_not_recruiting NCT03866109
A Study Evaluating Temferon in Patients With Glioblastoma & Unmethylated MGMT No drug interventions treatment 1 / 2 recruiting NCT04780009
Loupe-Based Intraoperative Fluorescence Imaging No drug interventions Not Available Not Available recruiting NCT04614909
Study of Pamiparib in Newly Diagnosed and rGBM treatment 0 recruiting NCT02966509
Engagement of Patients With Advanced Cancer No drug interventions health_services_research Not Available completed NCT06011109
Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab treatment 1 / 2 recruiting NCT06039709
Sonodynamic Therapy in Patients With Recurrent GBM treatment 1 recruiting NCT01985256
Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor treatment 1 completed NCT00508456
Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM treatment 1 terminated NCT02067156
Efficacy, Safety and CNS Exposure of G-202 (Mipsagargin) in Patients With Recurrent or Progressive Glioblastoma treatment 2 completed NCT04373785
NG101m Adjuvant Therapy in Glioblastoma Patients treatment 1 / 2 not_yet_recruiting NCT05756985
Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue No drug interventions Not Available Not Available not_yet_recruiting NCT00323115
Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme treatment 2 completed NCT01169415
Effects of Steroid Tapering on Functional Capacity and Neurocognition treatment Not Available withdrawn NCT01526837
Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence treatment 1 terminated NCT00904852
Safety Study of the Combination of Tandutinib With Temozolomide and Bevacizumab After Radiation and Temozolomide in Patients With Newly Diagnosed With Glioblastoma Multiforme treatment 1 withdrawn NCT02223052
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies treatment 1 completed NCT01631552
Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer treatment 1 / 2 completed NCT01280552
A Study of ICT-107 Immunotherapy in Glioblastoma Multiforme (GBM) No drug interventions treatment 2 completed NCT01756352
FET-PET for Evaluation of Response of Recurrent GBM to Avastin diagnostic 2 completed NCT06016452
A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma No drug interventions treatment 2 recruiting NCT01666600
NOA-12: BIBF1120 and R-RT in Glioblastoma treatment 1 / 2 terminated NCT02285959
Super-Selective Intraarterial Intracranial Infusion of Bevacizumab (Avastin) for Glioblastoma Multiforme treatment 1 recruiting NCT04671459
TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine No drug interventions treatment 2 active_not_recruiting NCT01135875
Laboratory Study of Early Tumor Markers in the Peripheral Blood of Glioblastoma Multiforme Patients No drug interventions Not Available Not Available completed NCT00589875
Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma treatment 2 completed NCT00751270
Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas treatment 1 completed NCT06329570
Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) treatment 1 / 2 not_yet_recruiting NCT01151670
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors supportive_care 1 completed NCT06451042
FET-PET/MRI Based Treatment Planning for Glioblastoma Multiforme in Post-Surgical Patients (FET-TREAT) No drug interventions Not Available Not Available recruiting NCT03311542
Expanded Access for Pembrolizumab (MK-3475) Not Available Not Available no_longer_available NCT01209442
Hypofractionated Intensity-Modulated Radiation Therapy With Temozolomide and Bevacizumab for Glioblastoma Multiforme treatment 2 completed NCT00412542
Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With Gliomas treatment 2 completed NCT03861299
The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients. No drug interventions treatment Not Available recruiting NCT01260506
Single-Arm Open-Label Multicenter Study of VB-111 in Patients With Recurrent Glioblastoma Multiforme treatment 1 / 2 completed NCT04874506
MBM-02 (Tempol) for the Treatment of Glioblastoma Multiforme (GBM) treatment 2 unknown_status NCT01475006
AMG 595 First-in-Human in Recurrent Gliomas No drug interventions treatment 1 completed NCT01186406
Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM) treatment 2 terminated NCT02010606
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma treatment 1 completed NCT04284306
Immunohistochemical Assessment of Programmed Death ligand1 and LC3B in GBM No drug interventions Not Available Not Available unknown_status NCT03980249
Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells treatment 0 withdrawn NCT01450449
Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme No drug interventions treatment 3 completed NCT00735436
A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM) treatment 2 terminated NCT02933736
Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients treatment 0 active_not_recruiting NCT03050736
Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression treatment 2 active_not_recruiting NCT06418113
Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma No drug interventions treatment 1 recruiting NCT05551013
Treatment of Recurrent GBM With APG-157 Via Expanded Access Not Available Not Available no_longer_available NCT05375318
BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels No drug interventions Not Available Not Available unknown_status NCT01351519
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors treatment 2 terminated NCT05095441
A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma No drug interventions treatment 1 not_yet_recruiting NCT05402241
IRD at Admission Predicts Survival of GBM Patients - a Prospective Pilot Study No drug interventions Not Available Not Available completed NCT00544817
Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma Multiforme treatment 2 completed NCT00923117
Sunitinib to Treat Recurrent Brain Cancer treatment 2 terminated NCT01508117
Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) Patients treatment 2 terminated NCT01205334
Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme No drug interventions treatment 1 / 2 terminated NCT01956734
Virus DNX2401 and Temozolomide in Recurrent Glioblastoma No drug interventions treatment 1 completed NCT03072134
Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma No drug interventions treatment 1 completed NCT03235934
Glycemic Impact on Glioblastoma Outcomes No drug interventions Not Available Not Available withdrawn NCT02780024
Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM treatment 2 active_not_recruiting NCT01468324
AZD7451 for Recurrent Gliomas No drug interventions treatment 1 completed NCT06218524
The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM treatment 2 not_yet_recruiting NCT02885324
Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children treatment 2 terminated NCT01269424
BG & TMZ Therapy of Glioblastoma Multiforme treatment 1 completed NCT00677716
Dose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First Relapse No drug interventions treatment 2 completed NCT00402116
Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients treatment 1 / 2 completed NCT04446416
Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients treatment Not Available completed NCT00990496
A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM) treatment 1 terminated NCT00591058
Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma treatment 1 unknown_status NCT02704858
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma treatment 1 / 2 recruiting NCT02540135
Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma No drug interventions other Not Available withdrawn NCT02590263
Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma treatment 1 / 2 completed NCT02006563
Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors No drug interventions Not Available Not Available completed NCT04492163
Open-Label Pilot Study of OPTUNE® With High Density Transducer Arrays for the Treatment of Recurrent GBM No drug interventions treatment 2 completed NCT00050986
Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme treatment 1 / 2 completed NCT00515086
Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM) treatment 2 terminated NCT00187486
Safety and Efficacy Study of Tarceva, Temodar, and Radiation Therapy in Patients With Newly Diagnosed Brain Tumors treatment 2 completed NCT00076986
The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme treatment 3 completed NCT01124539
Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcoma treatment 2 unknown_status NCT03506139
Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma No drug interventions treatment 2 withdrawn NCT01474239
A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma treatment 2 completed NCT01290939
Bevacizumab and Lomustine for Recurrent GBM treatment 3 completed NCT01923922
CT Perfusion in the Prognostication of Cerebral High Grade Glioma No drug interventions diagnostic Not Available completed NCT02926222
Regorafenib in Relapsed Glioblastoma treatment 2 completed NCT02441322
Evaluating Therapeutic Response to Novo-TTF No drug interventions health_services_research Not Available completed NCT01353625
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies. treatment 1 completed NCT01778530
TRC105 for Recurrent Glioblastoma treatment 2 terminated NCT01301430
Parvovirus H-1 (ParvOryx) in Patients With Progressive Primary or Recurrent Glioblastoma Multiforme. treatment 1 / 2 completed NCT00967330
A Study of Avastin (Bevacizumab) and Irinotecan Versus Temozolomide Radiochemistry in Patients With Glioblastoma treatment 2 completed NCT05353530
Phase I Study of IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma (IMPACT) No drug interventions treatment 1 recruiting NCT00262730
Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM treatment 2 completed NCT03862430
A Phase 2 Study of NanO2(TM) Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM treatment 2 recruiting NCT02052648
Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors treatment 1 / 2 completed NCT02586857
A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM) treatment 1 / 2 active_not_recruiting NCT00024557
Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients treatment 1 completed NCT00635557
Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme treatment 1 / 2 unknown_status NCT05565326
Response Assessment During MR-guided Radiation Therapy for Glioblastoma No drug interventions Not Available Not Available recruiting NCT02945826
uPAR-PET/MRI in Glioblastoma Multiforme No drug interventions diagnostic 2 unknown_status NCT01268566
A Study of MEDI-575 in Subjects With Recurrent Glioblastoma Multiforme treatment 2 completed NCT01044966
A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma treatment 1 / 2 terminated NCT02498665
A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies treatment 1 completed NCT02176720
Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma No drug interventions diagnostic 1 terminated NCT04810182
Regorafenib in Patients With Relapsed Glioblastoma. IOV-GB-1-2020 REGOMA-OSS Not Available Not Available completed NCT05063682
The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients No drug interventions treatment 1 unknown_status NCT01281982
(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas No drug interventions Not Available Not Available terminated NCT00892931
Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme treatment 2 completed NCT06283927
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) Not Available Not Available recruiting NCT01112527
PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma treatment 2 completed NCT06585527
Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma No drug interventions treatment 1 recruiting NCT05864976
Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning No drug interventions Not Available Not Available recruiting NCT04450160
Trial of AEO in New Glioblastoma (GBM) treatment 2 unknown_status NCT05769660
A Study to Evaluate Safety and Efficacy of BEY1107 in Combination With Temozolomide in Patients With Recurrent or Progressive Glioblastoma Multiforme (GBM) treatment 1 recruiting NCT04321694
Expanded Access for KHK2455 Not Available Not Available no_longer_available NCT00501891
Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma treatment 2 completed NCT01115491
A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme treatment 2 completed NCT00104091
Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors No drug interventions treatment 2 completed NCT01752491
A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme treatment 1 active_not_recruiting NCT06241391
Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas No drug interventions diagnostic Not Available not_yet_recruiting NCT02717962
Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting treatment 2 active_not_recruiting NCT00943462
Study of 18F-FEC for Positron Emission Tomography-Computed Tomography (PET-CT) Imaging of GBM Not Available Not Available withdrawn NCT01837862
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas treatment 1 / 2 completed NCT02365662
A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor No drug interventions treatment 1 terminated NCT04776980
Multimodality MRI and Liquid Biopsy in GBM No drug interventions diagnostic 0 withdrawn NCT01711580
Re-irradiation of High Grade Gliomas: a Quality of Life Study No drug interventions Not Available Not Available withdrawn NCT02296580
A Feasibility Study of the Nativis Voyager® System in Patients With Recurrent Glioblastoma Multiforme (GBM) No drug interventions treatment Not Available completed NCT00704080
A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas treatment 1 completed NCT05328089
Vacuolar ATPase and Drug Resistance of High Grade Gliomas No drug interventions Not Available Not Available recruiting NCT02049489
A Study of ICT-121 Dendritic Cell Vaccine in Recurrent Glioblastoma No drug interventions treatment 1 completed NCT02781792
Temozolomide Chronotherapy for High Grade Glioma treatment 2 completed NCT04900792
A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma treatment 1 recruiting NCT01091792
Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM) basic_science 0 completed NCT01811992
Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma No drug interventions treatment 1 completed NCT05450744
131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2) treatment 1 recruiting NCT02937844
Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme treatment 1 unknown_status NCT02850744
Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients treatment 2 terminated NCT04471844
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM No drug interventions treatment Not Available active_not_recruiting NCT03834740
A Phase 0 /II Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection treatment 0 completed NCT01884740
Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22 treatment 1 / 2 terminated NCT00968240
Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) treatment 1 completed NCT03310372
Concomitant Association of Ultrafractionated Brain Irradiation - Temozolomide in Inoperable Primary Glioblastoma Multiforme treatment 2 completed NCT01089868
Usefulness of Therapy Monitoring by Means of [(18)F]Fluoroethyltyrosine-Positron Emission Tomography (FET-PET) in Glioblastoma Multiforme Patients No drug interventions Not Available Not Available completed NCT00045968
Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer treatment 3 unknown_status NCT01588769
A Phase I Study to Investigate Tolerability and Efficacy of ALECSAT Administered to Glioblastoma Multiforme Patients treatment 1 completed NCT02722512
Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine treatment 1 terminated NCT04608812
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection treatment 1 terminated NCT00792012
A Dose Per Fraction Escalation Trial of Hypofractionated IMRT With Temozolomide for Newly Diagnosed Glioblastoma treatment 1 completed NCT00456612
Radiosurgery for Glioblastoma Multiforme No drug interventions treatment 1 / 2 terminated NCT01317212
Dose-Escalation Study of Carboplatin Administration Into the Brain for Glioblastoma Multiforme treatment 1 withdrawn NCT00083512
Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme No drug interventions Not Available Not Available recruiting NCT02898012
Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status treatment 2 completed NCT01564914
A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab in Patients With Glioblastoma treatment 2 completed NCT02047214
Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy treatment 2 terminated NCT03075514
Ketogenic Diets as an Adjuvant Therapy in Glioblastoma No drug interventions treatment Not Available completed NCT01285414
Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme treatment 2 completed NCT03722355
Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma treatment 3 completed NCT03865355
Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients No drug interventions Not Available Not Available recruiting NCT01117155
A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas No drug interventions Not Available Not Available withdrawn NCT02344355
A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme treatment 2 active_not_recruiting NCT02060955
Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan treatment 2 terminated NCT03344250
Phase I EGFR BATs in Newly Diagnosed Glioblastoma treatment 1 active_not_recruiting NCT02510950
Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma treatment 1 terminated NCT00473408
The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas No drug interventions Not Available Not Available terminated NCT00548938
Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM treatment 2 terminated NCT02974738
A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) treatment 1 active_not_recruiting NCT03419403
UNITE Study: Understanding New Interventions With GBM ThErapy treatment 3 terminated NCT00243490
Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors No drug interventions treatment 2 withdrawn NCT00093964
Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor) treatment 2 completed NCT03119064
BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastoma treatment 1 / 2 terminated NCT00734864
Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma No drug interventions treatment 1 withdrawn NCT02619864
mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme treatment 1 completed NCT00509821
Enzastaurin Before and Concomitant With Radiation, Followed by Enzastaurin in Participants With Newly Diagnosed Glioblastoma treatment 2 completed NCT06562621
Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma treatment 1 / 2 completed NCT06271421
NanoTherm In Adjuvant Therapy of Glioblastoma Multiforme treatment Not Available recruiting NCT04712721
Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. No drug interventions other 0 terminated NCT04277221
ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM) No drug interventions treatment 3 unknown_status NCT05222802
A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1) No drug interventions treatment 1 active_not_recruiting NCT02546102
Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma No drug interventions treatment 3 suspended NCT01567202
Study of DC Vaccination Against Glioblastoma No drug interventions treatment 2 unknown_status NCT01308684
A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma treatment 1 completed NCT00064779
Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma treatment 1 completed NCT05366179
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc No drug interventions treatment 1 recruiting NCT00535379
SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme treatment 2 unknown_status NCT00041587
Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma treatment 1 / 2 completed NCT00686387
Establishment of a Brain and Spinal Tumor Tissue Bank No drug interventions Not Available Not Available unknown_status NCT04482933
HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma treatment 2 not_yet_recruiting NCT04588454
18F-PSMA PET/CT for Visualization of Glioblastoma Multiforme No drug interventions diagnostic Not Available unknown_status NCT00747253
Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors No drug interventions treatment 1 completed NCT00892177
Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme treatment 2 completed NCT03382977
Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects treatment 1 / 2 recruiting NCT01144247
Cellular Immunotherapy Study for Brain Cancer No drug interventions treatment 1 completed NCT05686798
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. No drug interventions treatment 1 recruiting NCT04765098
Tamoxifen Versus Etoposide After First Recurrence in GBM Patients treatment 2 recruiting NCT03861598
Carvedilol With Chemotherapy in Second Line Glioblastoma and Response of Circulating Tumor Cells treatment 0 terminated NCT01113398
AMG 102 and Avastin for Recurrent Malignant Glioma treatment 2 completed NCT02331498
Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme treatment 1 / 2 recruiting NCT05182905
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients No drug interventions treatment 0 recruiting NCT03849105
131I-IPA and Concurrent XRT in Recurrent GBM No drug interventions treatment 1 / 2 completed NCT04726397
UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: A Phase 2 Trial No drug interventions treatment Not Available active_not_recruiting NCT04790097
FET-PET Directed Simultaneous In-field Boost for Primary GBM No drug interventions treatment Not Available completed NCT00031083
Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas No drug interventions treatment 1 completed NCT00805961
RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM treatment 2 completed NCT00683761
A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma No drug interventions treatment 1 / 2 unknown_status NCT00394628
AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme treatment 1 / 2 unknown_status NCT02366728
DC Migration Study for Newly-Diagnosed GBM treatment 2 completed NCT04327011
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511 treatment 1 terminated NCT00768911
CT-322 in Combination With Radiation Therapy and Temozolomide to Treat Newly Diagnosed Glioblastoma Multiforme treatment 1 unknown_status NCT04116411
A Clinical Trial Evaluating the Efficacy of Valganciclovir in Glioblastoma Patients treatment 2 unknown_status NCT00038493
Temozolomide and SCH66336 for Recurrent Glioblastoma Multiforme treatment 2 completed NCT03025893
A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme treatment 2 / 3 unknown_status NCT01902771
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors No drug interventions treatment 1 terminated NCT02026271
A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma treatment 1 completed NCT02663271
TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma treatment 2 terminated NCT04421378
A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma treatment 1 / 2 terminated NCT00224978
Chloroquine for Treatment of Glioblastoma Multiforme treatment 3 completed NCT03027388
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma basic_science 2 completed NCT01213407
Dendritic Cell Cancer Vaccine for High-grade Glioma treatment 2 completed NCT03561207
3D Prediction of Patient-Specific Response No drug interventions Not Available Not Available active_not_recruiting NCT00943007
Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors No drug interventions treatment Not Available completed NCT00995007
A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas treatment 2 completed NCT04222309
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) No drug interventions treatment 1 suspended NCT00114309
131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma treatment 2 unknown_status NCT01316809
AZD8055 for Adults With Recurrent Gliomas treatment 1 completed NCT00916409
Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) treatment 3 completed NCT00645385
Examination of Changes on Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) in Patients Who Receive Gliadel Wafers During Initial Surgery for Glioblastoma Multiforme. Response or Failure to Gliadel Wafers for Subjects With Glioblastoma Multiforme. No drug interventions Not Available Not Available withdrawn NCT05958485
A Close Examination of Patient Experiences in Glioblastoma Multiforme Clinical Research No drug interventions Not Available Not Available not_yet_recruiting NCT01933815
Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma treatment 1 / 2 suspended NCT01071837
APG101 in Glioblastoma treatment 2 completed NCT00879437
Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma treatment 2 completed NCT02378532
The Addition of Chloroquine to Chemoradiation for Glioblastoma treatment 1 completed NCT05708352
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment No drug interventions treatment 2 recruiting NCT03225300
Simultaneous Integrated Boost in Malignant Glioma Patients Treated With Chemoradiation No drug interventions treatment Not Available unknown_status NCT04295759
INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas treatment 1 active_not_recruiting NCT03363659
Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme treatment 2 terminated NCT04825275
Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial treatment 0 recruiting NCT04977375
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma treatment 1 / 2 recruiting NCT02928575
Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma treatment 2 unknown_status NCT00154375
Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma treatment 3 completed NCT05432375
Study of Tinostamustine for Adjuvant Treatment of Glioblastoma treatment 0 active_not_recruiting NCT03149575
VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM treatment 3 terminated NCT00024570
Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma treatment 1 / 2 completed NCT00441142
Zactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain Tumors treatment 1 / 2 completed NCT00555399
Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM) treatment 1 / 2 terminated NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion treatment 0 not_yet_recruiting NCT04530006
Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma No drug interventions diagnostic Not Available recruiting NCT02769806
Advanced Perfusion MRI of Treatment Response and Progression in Glioblastoma No drug interventions Not Available Not Available terminated NCT04869449
Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas treatment 0 recruiting NCT02017249
Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme treatment 1 completed NCT00650949
Efficacy Study of CYT997 in Combination With Carboplatin in Glioblastoma treatment 1 / 2 terminated NCT02550249
Neoadjuvant Nivolumab in Glioblastoma treatment 2 completed NCT05624736
Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning No drug interventions Not Available Not Available recruiting NCT04752813
A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB) treatment 2 recruiting NCT01540513
PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404 No drug interventions diagnostic Not Available completed NCT05076513
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma treatment 0 recruiting NCT03152318
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 treatment 1 recruiting NCT00301418
Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma treatment 1 / 2 completed NCT04845919
Sonodynamic Therapy With ExAblate System in Glioblastoma Patients other 2 not_yet_recruiting NCT01777919
Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform treatment 2 unknown_status NCT03170141
Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme No drug interventions treatment 1 enrolling_by_invitation NCT06157541
T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma treatment 1 / 2 recruiting NCT04224441
Repurposing Chlorpromazine in the Treatment of Glioblastoma treatment 2 unknown_status NCT00979017
Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme treatment 2 completed NCT00800917
A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma Multiforme treatment 2 completed NCT05864534
Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma treatment 2 recruiting NCT03175224
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors treatment 2 recruiting NCT01180816
Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA treatment 1 completed NCT04606316
Surgical Nivolumab And Ipilimumab For Recurrent GBM treatment 1 active_not_recruiting NCT03626896
Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients No drug interventions device_feasibility Not Available completed NCT01967758
Phase I Study of Safety and Immunogenicity of ADU-623 treatment 1 completed NCT03896958
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) No drug interventions Not Available Not Available unknown_status NCT03212235
Hypofractionated Radiation Therapy for Glioblastoma No drug interventions treatment 2 unknown_status NCT01294735
Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1) treatment 1 completed NCT01290263
Amgen 386 for Recurrent Glioblastoma treatment 1 / 2 completed NCT03225963
Application of Proteome Profiler Antibody Arrays to Find Angiogenetic Predictors in Glioma Paitents. No drug interventions Not Available Not Available unknown_status NCT01402063
PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation treatment 2 completed NCT06533163
Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial No drug interventions treatment Not Available not_yet_recruiting NCT03276286
Nativis Voyager for Newly Diagnosed GBM No drug interventions device_feasibility Not Available completed NCT03596086
HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM treatment 1 / 2 recruiting NCT00615186
Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy treatment 3 terminated NCT04195139
Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM treatment 2 active_not_recruiting NCT01120639
Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform treatment 1 / 2 completed NCT00400322
Efficacy and Safety of Valcyte® as an add-on Therapy in Patients With Malignant Glioblastoma and Cytomegalovirus (CMV) Infection treatment Not Available completed NCT04250922
LAM561 With RT and TMZ for Adults With Glioblastoma treatment 2 / 3 active_not_recruiting NCT06146725
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202) No drug interventions Not Available Not Available recruiting NCT05084430
Study of Pembrolizumab and M032 (NSC 733972) treatment 1 / 2 recruiting NCT05934630
Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors No drug interventions Not Available Not Available active_not_recruiting NCT02078648
Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme treatment 1 / 2 completed NCT03916757
V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer No drug interventions treatment 2 unknown_status NCT03707457
Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma treatment 1 terminated NCT00311857
Safety Study of Cetuximab, Radiotherapy and Temozolomide in Primary Glioblastoma Multiforme(GERT) treatment 1 / 2 unknown_status NCT05052957
hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) treatment 2 recruiting NCT03370926
FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy No drug interventions Not Available Not Available unknown_status NCT02386826
INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme treatment 1 completed NCT02709226
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma No drug interventions treatment 1 completed NCT03401866
Multi-site Validation and Application of a Consensus DSC-MRI Protocol No drug interventions diagnostic Not Available unknown_status NCT02146066
Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221 Not Available Not Available available NCT00479765
A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma treatment 1 / 2 terminated NCT02853565
A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme treatment 1 completed NCT02414165
The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma treatment 2 / 3 terminated NCT05561374
Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma treatment 1 recruiting NCT01808820
Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma treatment 1 completed NCT04489420
Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM treatment 1 terminated NCT01929720
Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors No drug interventions supportive_care Not Available completed NCT02104882
INTRAGO-Intraoperative Radiotherapy for Glioblastoma - a Phase I/II Study No drug interventions treatment 1 / 2 completed NCT06466031
Application of MET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme No drug interventions treatment Not Available not_yet_recruiting NCT05281731
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma No drug interventions diagnostic Not Available recruiting NCT02029573
Efficacy and Safety of Atorvastatin in Combination With Radiotherapy and Temozolomide in Glioblastoma treatment 2 completed NCT04444427
Evaluation of GLR2007 for Advanced Solid Tumors No drug interventions treatment 1 / 2 completed NCT00089427
IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma treatment 1 completed NCT04978727
A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma treatment 1 recruiting NCT01110876
Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM) treatment 1 / 2 terminated NCT02296476
A Dose-finding Study of Birabresib (MK-8628) in Participants With Recurrent Glioblastoma Multiforme (MK-8628-002) treatment 2 terminated NCT00116376
Study of AEE788 in Patients With Recurrent/Relapse Glioblastoma Multiforme (GBM) treatment 1 / 2 completed NCT06353360
TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma. treatment 2 recruiting NCT01349660
Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme treatment 1 / 2 completed NCT00504660
6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients treatment 2 completed NCT02772094
Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas) No drug interventions treatment 2 unknown_status NCT01470794
Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor treatment 1 completed NCT01865162
Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study No drug interventions treatment 1 completed NCT02844062
Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme treatment 1 unknown_status NCT00730262
Efficacy Study of TLN-4601 in Patients With Recurring Glioblastoma Multiforme treatment 2 terminated NCT03642080
MRI Predictors of Response to Tumor Treating Fields No drug interventions Not Available Not Available unknown_status NCT04528680
Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma treatment 1 / 2 recruiting NCT06054529
Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients No drug interventions Not Available Not Available recruiting NCT04610229
Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. No drug interventions treatment Not Available completed NCT03630289
Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM No drug interventions treatment Not Available active_not_recruiting NCT00209989
Phase II Trial to Assess the Radiosensitizing Effect of ZARNESTRA in Patients With Glioblastoma Multiforme treatment 2 completed NCT00267592
Safety and Efficacy of Talampanel in Glioblastoma Multiforme treatment 2 completed NCT01290692
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma treatment 2 completed NCT01587144
Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM) treatment 2 terminated NCT01006044
Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection No drug interventions treatment 2 completed NCT00797940
Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1) treatment 2 withdrawn NCT02663440
Trial of Hypofractionated Intensity Modulated Radiation Therapy With Temozolomide and Granulocyte-macrophage Colony-stimulating Factor for Patients With Newly Diagnosed Glioblastoma Multiforme treatment 2 unknown_status NCT05879367
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma treatment 1 recruiting NCT02286167
Glioma Modified Atkins-based Diet in Patients With Glioblastoma No drug interventions other Not Available completed NCT00062504
Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas treatment 2 terminated NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors diagnostic 2 recruiting NCT02465268
Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme treatment 2 completed NCT02864368
Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens treatment 1 terminated NCT05908669
Deuterium Metabolic Imaging to Assess Radiotherapy Changes in Glioblastoma Multiforme No drug interventions Not Available Not Available enrolling_by_invitation NCT03780569
TTFields Together With Temozolomide and Radiotherapy in Patients With Newly Diagnosed GBM treatment Not Available unknown_status NCT01873469
Impact of [11C]-Methionine PET/MRI for Individual Tailoring Postoperative Radiochemotherapy for Glioblastoma Multiforme No drug interventions Not Available Not Available completed NCT05500612
MRI Hypoxia Study for Glioblastoma Multiforme (GBM) Radiation Therapy No drug interventions Not Available Not Available not_yet_recruiting NCT02815410
Validation of the Role of Levetiracetam for Newly Diagnosed GBM Patients treatment 2 unknown_status NCT01386710
Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma treatment 1 / 2 suspended NCT00590681
Bevacizumab and Temozolomide Following Radiation and Chemotherapy for Newly Diagnosed Glioblastoma Multiforme treatment 2 completed NCT01435395
Trial of Temozolomide, Bevacizumab Plus Bortezomib for Recurrent Glioblastoma Multiforme treatment 1 completed NCT01800695
Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme treatment 1 completed NCT05608395
11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET) diagnostic 2 active_not_recruiting NCT05495295
First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours No drug interventions treatment 1 recruiting NCT00589095
Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities No drug interventions Not Available Not Available terminated NCT02858895
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma treatment 2 completed NCT03582514
PreOperative Brain Irradiation in Glioblastoma No drug interventions treatment 1 recruiting NCT00409214
Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma treatment 2 completed NCT04765514
Chemoradiotherapy Versus Biomarker-Guided Therapy for Elderly and Frail GBM Patients treatment 2 recruiting NCT03332355
Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2 treatment 1 terminated NCT01081223
Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma treatment 1 / 2 completed NCT02502708
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors treatment 1 completed NCT05218408
CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type treatment 1 / 2 withdrawn NCT06146738
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) No drug interventions Not Available Not Available recruiting NCT00984438
Surgery With Implantable Biodegradable Carmustine (BCNU) Wafer Followed by Chemo for Patients With Recurrent Glioblastoma Multiforme treatment 1 / 2 withdrawn NCT00031538
Genetic Analysis of Brain Tumors No drug interventions Not Available Not Available terminated NCT02751138
Determination of Immune Phenotype in Glioblastoma Patients No drug interventions Not Available Not Available completed NCT06595186
JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM) treatment 2 recruiting NCT03213002
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM treatment 1 / 2 recruiting NCT02202993
TAU-2014-1: Mibefradil and Hypofractionated Re-Irradiation Therapy in Recurrent GBM treatment 1 completed NCT01238237
Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA treatment 1 completed NCT04587830
ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme treatment 1 recruiting NCT01109095
CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM No drug interventions treatment 1 completed NCT04019002
Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma No drug interventions diagnostic 1 active_not_recruiting NCT02654041
Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients supportive_care 2 terminated NCT01788280
Preliminary Assessment of [18F] Fluciclatide (GE [18F]AH111585) in Glioblastoma Multiforme Treated With Bevacizumab treatment 2 withdrawn