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Displaying results 4291 - 4300 of 10000 in total
  1. Target

    Glucose-6-phosphatase catalytic subunit 1

    go.drugbank.com/bio_entities/BE0013006
    TargetHumans

    Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. … Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis.

    Polypeptides: Glucose-6-phosphatase catalytic subunit 1Synonyms: G-6-Pase, Glucose-6-phosphatase
  2. Target

    Short transient receptor potential channel 6

    go.drugbank.com/bio_entities/BE0020965
    TargetHumans

    Non-selective, calcium-permeable cation channel (PubMed:19936226, PubMed:23291369, PubMed:26892346, PubMed:9930701). Mediates calcium entry following G(q)-coupled receptor or receptor tyrosine kinase activation, which triggers phospholip...

    Polypeptides: Short transient receptor potential channel 6Synonyms: TRP-6, Transient receptor protein 6
  3. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. … It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.

    Mixtures: ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 5 ADET, ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADETProducts: T-VAC 0,5 ML IM ENJEKSIYON IÇIN SÜSPANSIYON IÇEREN AMPUL, TETAVAX single dose, suspension for injection in a prefilled syringe
  4. Target

    4-aminobutyrate aminotransferase, mitochondrial

    go.drugbank.com/bio_entities/BE0000253
    TargetEnzymeHumans

    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively (PubMed:10407778, PubMed:15528998). Can also convert delta-aminovalerate and beta-alanine...

    Polypeptides: 4-aminobutyrate aminotransferase, mitochondrial
  5. Target

    Retinol-binding protein 4

    go.drugbank.com/bio_entities/BE0000314
    CarrierTargetHumans

    Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates ...

    Polypeptides: Retinol-binding protein 4
  6. Target

    Fibroblast growth factor 4

    go.drugbank.com/bio_entities/BE0000326
    TargetHumans

    Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. May play a role in embryonic molar tooth bud d...

    Polypeptides: Fibroblast growth factor 4Synonyms: FGF-4, HBGF-4
  7. Target

    Metabotropic glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000833
    TargetHumans

    G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits ad...

    Polypeptides: Metabotropic glutamate receptor 4
  8. Target

    Leukotriene A-4 hydrolase

    go.drugbank.com/bio_entities/BE0001680
    TargetHumans

    Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4) (PubMed:1191...

    Polypeptides: Leukotriene A-4 hydrolaseSynonyms: LTA-4 hydrolase, Leukotriene A(4) hydrolase
  9. Target

    UDP-glucose 4-epimerase

    go.drugbank.com/bio_entities/BE0001901
    TargetEnzymeEscherichia coli (strain K12)

    Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. It is only active on UDP-galactose and UDP-glucose.

    Polypeptides: UDP-glucose 4-epimeraseSynonyms: UDP-galactose 4-epimerase
  10. Target

    dTDP-4-dehydrorhamnose reductase

    go.drugbank.com/bio_entities/BE0001971
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. RmlD uses NADH and NADPH nearly equally well.

    Polypeptides: dTDP-4-dehydrorhamnose reductaseSynonyms: dTDP-6-deoxy-L-lyxo-4-hexulose reductase, dTDP-4-keto-L-rhamnose reductase