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Ephrin type-A receptor 3
go.drugbank.com/bio_entities/BE0009437TargetHumansHighly promiscuous for ephrin-A ligands it binds preferentially EFNA5 (By similarity). … Also activated by EFNA1, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development (PubMed:12794130). Involved in the retinotectal mapping of neurons.
Polypeptides: Ephrin type-A receptor 3Synonyms: EPH-like kinase 4Ephrin type-A receptor 6
go.drugbank.com/bio_entities/BE0009439TargetHumansReceptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
Polypeptides: Ephrin type-A receptor 6ATP-dependent RNA helicase A
go.drugbank.com/bio_entities/BE0014303TargetHumansPlays a role as a transcriptional coactivator acting as a bridging factor between polymerase II holoenzyme and transcription factors or cofactors, such as BRCA1, CREBBP, RELA and SMN1 (PubMed:11038348, … Plays a role in mRNA translation (PubMed:28355180).
Polypeptides: ATP-dependent RNA helicase ASynonyms: RNA helicase ADimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalIt is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants.
Mixtures: PANKREOFLAT 170/310 MG GRANÜL (22x2 g poşet), E-Z-gas IICategories: Compounds used in a research, industrial, or household settingCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnCanrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: POTASSIO CANRENOATO EG, Aldactone 200 mg/ 10 ml InjektionslösungAcetyl-coenzyme A synthetase, cytoplasmic
go.drugbank.com/bio_entities/BE0000350TargetEnzymeHumansCan also utilize propionate with a much lower affinity (PubMed:38369012). Catalyzes the conversion of lactate into lactoyl-CoA (PubMed:39561764). … Acts as a chromatin-bound transcriptional coactivator that up-regulates histone acetylation and expression of neuronal genes (By similarity).
Polypeptides: Acetyl-coenzyme A synthetase, cytoplasmicHydroxyacyl-coenzyme A dehydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0000377TargetHumansPlays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity) … Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion
Polypeptides: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialSynonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenaseEphrin type-A receptor 2
go.drugbank.com/bio_entities/BE0000841TargetHumansWith ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis … May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.
Polypeptides: Ephrin type-A receptor 2Ribose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001557TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A