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4-hydroxy-tetrahydrodipicolinate reductase
go.drugbank.com/bio_entities/BE0001986TargetEscherichia coli (strain K12)Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and NADPH as a reductant, with NADH being twice as effective as NADPH.
Polypeptides: 4-hydroxy-tetrahydrodipicolinate reductaseFunction: 4-hydroxy-tetrahydrodipicolinate reductaseBeta-1,4-galactosyltransferase 4
go.drugbank.com/bio_entities/BE0002263TargetHumans[->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer (PubMed:17690104). … Transfers Gal residue via a beta1->4 linkage to terminal 6-O-sulfoGlcNAc within the LacNac unit of core 2 O-glycans forming 6-sulfo-sialyl-Lewis X (sLex).
Polypeptides: Beta-1,4-galactosyltransferase 4Synonyms: Beta-1,4-GalTase 4, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 44-chlorobenzoyl CoA dehalogenase
go.drugbank.com/bio_entities/BE0002495TargetPseudomonas sp. DJ-12Polypeptides: 4-chlorobenzoyl CoA dehalogenase4'-phosphopantetheinyl transferase sfp
go.drugbank.com/bio_entities/BE0002687TargetBacillus subtilis (strain 168)Activates the seven peptidyl carrier protein (PCP) domains of the first three subunits (SrfAA, SrfAB and SrfAC) of surfactin synthetase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (
Polypeptides: 4'-phosphopantetheinyl transferase sfpPutative inactive carboxylesterase 4
go.drugbank.com/bio_entities/BE0004349TargetHumansHas no esterase activity
Polypeptides: Putative inactive carboxylesterase 4Adenylate kinase 4, mitochondrial
go.drugbank.com/bio_entities/BE0004780EnzymeHumansBroad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions (PubMed:19073142, PubMed:19766732, PubMed:23416111, PubMed:24767988). Similar to ...
Polypeptides: Adenylate kinase 4, mitochondrialBone morphogenetic protein 4
go.drugbank.com/bio_entities/BE0009000TargetHumansGrowth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (PubMed:31363885). Acts in concert with PTHLH/PTHRP to stim...
Polypeptides: Bone morphogenetic protein 4Synonyms: BMP-4Somatostatin receptor type 4
go.drugbank.com/bio_entities/BE0009273TargetHumansReceptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate re...
Polypeptides: Somatostatin receptor type 4Synonyms: SS-4-RPhosphatidylinositol 4-kinase beta
go.drugbank.com/bio_entities/BE0009513TargetHumansPhosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phospho...
Polypeptides: Phosphatidylinositol 4-kinase betaSynonyms: PtdIns 4-kinase betaDelta-like protein 4
go.drugbank.com/bio_entities/BE0010485TargetHumansInvolved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313...
Polypeptides: Delta-like protein 4Synonyms: Drosophila Delta homolog 4