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Displaying results 4361 - 4370 of 10000 in total
  1. Pathway

    Phosphatidylethanolamine Biosynthesis PE(24:1(15Z)/14:0)

    smpdb.ca/view/SMP0015867
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  2. Pathway

    Phosphatidylethanolamine Biosynthesis PE(24:1(15Z)/16:0)

    smpdb.ca/view/SMP0015870
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  3. Pathway

    Acylcarnitine (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoylcarnitine

    smpdb.ca/view/SMP0124345
    Metabolic

    (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoyl-CoA reacts with L-carnitine to form (9E,11E,15Z)-9-hydroxyoctadeca-9,11,15-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Pathway

    Acylcarnitine (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoylcarnitine

    smpdb.ca/view/SMP0124346
    Metabolic

    (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoyl-CoA reacts with L-carnitine to form (9Z,12Z,15Z)-17-hydroxyoctadeca-9,12,15-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  5. Drug

    Rurioctocog alfa pegol

    go.drugbank.com/drugs/DB16007
    ApprovedInvestigational

    Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous … [L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant factor VIII produced by recombinant DNA technology from a Chinese hamster ovary cell line.

    Synonyms: Antihemophilic factor (recombinant), pegylated (mw 20000), Antihemophilic factor, pegylated (mw 20000) human sequence recombinant
  6. Drug

    Mercuric chloride

    go.drugbank.com/drugs/DB13765
    Experimental

    Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. … It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: bichlorure de mercure, dichlorure de mercure
  7. Drug

    Belantamab mafodotin

    go.drugbank.com/drugs/DB15719
    ApprovedInvestigationalWithdrawn

    [L53673] Later that year in October of 2025, belantamab was granded full approval by the FDA for the a similar indication to the Health Canada one. [L54331] … Belantamab mafodotin, or GSK2857916, is an afucosylated monoclonal antibody that targets B cell maturation antigen conjugated to the microtubule disrupter monomethyl auristatin-F (MMAF).

  8. Drug

    Imlifidase

    go.drugbank.com/drugs/DB15258
    ApprovedInvestigational

    [A225836] As a result, highly sensitized individuals experience marked delays on transplant lists due to the challenges associated with procuring an HLA compatible donor graft. … [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies.

  9. Drug

    Hexafluronium

    go.drugbank.com/drugs/DB00941
    Approved

    Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery.

  10. Drug

    Rucaparib

    go.drugbank.com/drugs/DB12332
    ApprovedInvestigational

    Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. … an androgen receptor–directed therapy, confirming clinical benefit for an indication that previously had accelerated approval.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index