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Displaying results 4391 - 4400 of 10000 in total
  1. Target

    Proteasome subunit beta type-4

    go.drugbank.com/bio_entities/BE0003918
    TargetHumans

    Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory parti...

    Polypeptides: Proteasome subunit beta type-4
  2. Target

    Pterin-4-alpha-carbinolamine dehydratase

    go.drugbank.com/bio_entities/BE0004555
    TargetHumans

    Involved in tetrahydrobiopterin biosynthesis (By similarity). Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription (By similarity). Regulates the di...

    Polypeptides: Pterin-4-alpha-carbinolamine dehydrataseSynonyms: 4-alpha-hydroxy-tetrahydropterin dehydratase
  3. Target

    Intracellular hyaluronan-binding protein 4

    go.drugbank.com/bio_entities/BE0004943
    TargetHumans

    Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). Acts via its association with EEF2/eEF2 factor ...

    Polypeptides: Intracellular hyaluronan-binding protein 4Synonyms: IHABP-4, Hyaluronan-binding protein 4
  4. Target

    Immunoglobulin heavy constant gamma 4

    go.drugbank.com/bio_entities/BE0005089
    TargetHumans

    Ig gamma-4 (IgG4) isotype does not elicit antibody-dependent cellular cytotoxicity (ADDC) or complement-dependent cytotoxicity (CDC).

    Polypeptides: Immunoglobulin heavy constant gamma 4Synonyms: Ig gamma-4 chain C region
  5. Target

    Inward rectifier potassium channel 4

    go.drugbank.com/bio_entities/BE0005187
    TargetHumans

    Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as externa...

    Polypeptides: Inward rectifier potassium channel 4Synonyms: Potassium channel, inwardly rectifying subfamily J member 4
  6. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0008383
    TargetStaphylococcus aureus

    Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit A
  7. Target

    Calcium-dependent protein kinase 4

    go.drugbank.com/bio_entities/BE0009256
    TargetPlasmodium falciparum (isolate 3D7)

    Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:19307175, PubMed:19666141). Plays a central role in the host erythrocyte...

    Polypeptides: Calcium-dependent protein kinase 4
  8. Target

    Sphingosine 1-phosphate receptor 4

    go.drugbank.com/bio_entities/BE0009882
    TargetHumans

    G protein-coupled receptor highly expressed in immune cells, where it regulates immune response and cytokine production. Functions as a receptor for the lysosphingolipid sphingosine-1-phosphate (S1P). Upon S1P binding, promotes regulator...

    Polypeptides: Sphingosine 1-phosphate receptor 4Synonyms: S1P receptor 4, S1P receptor Edg-6
  9. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. … PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation.

    Mixtures: Gavilyte G Tm, LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 MLCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  10. Target

    Probable L-ascorbate-6-phosphate lactonase UlaG

    go.drugbank.com/bio_entities/BE0004089
    TargetEscherichia coli (strain K12)

    Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions.

    Polypeptides: Probable L-ascorbate-6-phosphate lactonase UlaGFunction: L-ascorbate 6-phosphate lactonase activity