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Displaying results 4411 - 4420 of 10000 in total
  1. Target

    Cationic amino acid transporter 4

    go.drugbank.com/bio_entities/BE0000052
    TargetHumans

    Involved in the transport of the cationic amino acids (arginine, lysine and ornithine)

    Polypeptides: Cationic amino acid transporter 4Synonyms: CAT-4, Solute carrier family 7 member 4
  2. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000429
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit A
  3. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000798
    TargetEscherichia coli (strain K12)

    Topoisomerase IV is essential for chromosome segregation; it is the principal protein responsible for decatenating newly replicated chromosomes (PubMed:9334322). It relaxes supercoiled DNA (PubMed:12269820, PubMed:16023670, PubMed:213006...

    Polypeptides: DNA topoisomerase 4 subunit A
  4. Target

    Glutamate receptor ionotropic, kainate 4

    go.drugbank.com/bio_entities/BE0000827
    TargetHumans

    Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel. Cannot form functional channels on its own (PubMed:8263508). Shows channel activity only in heteromeric assembly with GRIK1, GRIK2 and GRIK3 sub...

    Polypeptides: Glutamate receptor ionotropic, kainate 4
  5. Target

    Carminomycin 4-O-methyltransferase DnrK

    go.drugbank.com/bio_entities/BE0001712
    TargetStreptomyces peucetius

    In vivo, catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the 4-O-position of carminomycin to form daunorubicin. … In vitro, it also methylates the anthracyclines rhodomycin D (10-carbomethoxy-13-deoxycarminomycin) and 13-deoxy-carminomycin at the 4-hydroxyl position.

    Polypeptides: Carminomycin 4-O-methyltransferase DnrKSynonyms: Anthracycline 4-O-methyltransferase
  6. Target

    Excitatory amino acid transporter 4

    go.drugbank.com/bio_entities/BE0002270
    TargetHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:26690923, PubMed:7791878). Functions as a symporter that transports one amino acid molecule toget...

    Polypeptides: Excitatory amino acid transporter 4Synonyms: Solute carrier family 1 member 6
  7. Target

    Interleukin-4 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002420
    TargetHumans

    Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation.

    Polypeptides: Interleukin-4 receptor subunit alphaSynonyms: IL-4 receptor subunit alpha
  8. Target

    Ephrin type-B receptor 4

    go.drugbank.com/bio_entities/BE0002453
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously to transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the ...

    Polypeptides: Ephrin type-B receptor 4
  9. Target

    DTDP-4-dehydrorhamnose 3,5-epimerase

    go.drugbank.com/bio_entities/BE0002995
    TargetStreptococcus suis

    Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseFunction: dTDP-4-dehydrorhamnose 3,5-epimerase activity
  10. Target

    Type-4 uracil-DNA glycosylase

    go.drugbank.com/bio_entities/BE0003080
    TargetThermus thermophilus

    Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair as well...

    Polypeptides: Type-4 uracil-DNA glycosylaseFunction: 4 iron, 4 sulfur cluster binding