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Displaying results 4451 - 4460 of 10000 in total
  1. Target

    Fibroblast growth factor receptor 4

    go.drugbank.com/bio_entities/BE0001203
    TargetHumans

    Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of

    Polypeptides: Fibroblast growth factor receptor 4Synonyms: FGFR-4
  2. Target

    dTDP-4-dehydrorhamnose 3,5-epimerase

    go.drugbank.com/bio_entities/BE0001669
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

    Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseSynonyms: dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
  3. Target

    Choline transporter-like protein 4

    go.drugbank.com/bio_entities/BE0002182
    TransporterHumans

    Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function … Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (PubMed

    Polypeptides: Choline transporter-like protein 4Synonyms: Solute carrier family 44 member 4
  4. Target

    dTDP-4-dehydrorhamnose 3,5-epimerase

    go.drugbank.com/bio_entities/BE0002506
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

    Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseSynonyms: dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
  5. Target

    dTDP-4-dehydrorhamnose 3,5-epimerase

    go.drugbank.com/bio_entities/BE0003322
    TargetMycobacterium tuberculosis

    Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. … peptidoglycan via a phosphodiester linkage.

    Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseSynonyms: dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
  6. Target

    DNA topoisomerase 4 subunit B

    go.drugbank.com/bio_entities/BE0003727
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit B
  7. Target

    Proteasome subunit beta type-4

    go.drugbank.com/bio_entities/BE0003918
    TargetHumans

    This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). … The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are

    Polypeptides: Proteasome subunit beta type-4
  8. Target

    Pterin-4-alpha-carbinolamine dehydratase

    go.drugbank.com/bio_entities/BE0004555
    TargetHumans

    Also acts as a coactivator for HNF1B-dependent transcription (PubMed:24204001)

    Polypeptides: Pterin-4-alpha-carbinolamine dehydrataseSynonyms: 4-alpha-hydroxy-tetrahydropterin dehydratase
  9. Target

    Intracellular hyaluronan-binding protein 4

    go.drugbank.com/bio_entities/BE0004943
    TargetHumans

    Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). … Plays a key role in ribosome hibernation in the mature oocyte by promoting ribosome stabilization (By similarity).

    Polypeptides: Intracellular hyaluronan-binding protein 4Synonyms: IHABP-4, Hyaluronan-binding protein 4
  10. Target

    Immunoglobulin heavy constant gamma 4

    go.drugbank.com/bio_entities/BE0005089
    TargetHumans

    Ig gamma-4 (IgG4) isotype does not elicit antibody-dependent cellular cytotoxicity (ADDC) or complement-dependent cytotoxicity (CDC). … In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding to a specific antigen trigger the clonal expansion and differentiation of B lymphocytes into

    Polypeptides: Immunoglobulin heavy constant gamma 4Synonyms: Ig gamma-4 chain C region