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Displaying results 4461 - 4470 of 10000 in total
  1. Target

    Stabilin-2

    go.drugbank.com/bio_entities/BE0004948
    TargetHumans

    Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Also acts, in different species, as a primary systemic scavenger receptor fo...

    Polypeptides: Stabilin-2Synonyms: FEEL-2, FAS1 EGF-like and X-link domain-containing adhesion molecule 2
  2. Target

    Fibrillin-2

    go.drugbank.com/bio_entities/BE0008694
    TargetHumans

    Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly.

    Polypeptides: Fibrillin-2
  3. Target

    Calsequestrin-2

    go.drugbank.com/bio_entities/BE0008695
    TargetHumans

    Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction.

    Polypeptides: Calsequestrin-2
  4. Target

    Calmodulin-2

    go.drugbank.com/bio_entities/BE0008705
    TargetHumans

    Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding (PubMed:16760425, PubMed:26969752, PubMed:2716569...

    Polypeptides: Calmodulin-2
  5. Target

    Transgelin-2

    go.drugbank.com/bio_entities/BE0009122
    TargetHumans

    Polypeptides: Transgelin-2
  6. Target

    Caspase-2

    go.drugbank.com/bio_entities/BE0013189
    TargetHumans

    Is a regulator of the cascade of caspases responsible for apoptosis execution (PubMed:11156409, PubMed:15073321, PubMed:8087842). Might function by either activating some proteins required for cell death or inactivating proteins necessar...

    Polypeptides: Caspase-2Synonyms: CASP-2, NEDD-2
  7. Target

    Sestrin-2

    go.drugbank.com/bio_entities/BE0013521
    TargetHumans

    Functions as an intracellular leucine sensor that negatively regulates the mTORC1 signaling pathway through the GATOR complex (PubMed:18692468, PubMed:25263562, PubMed:25457612, PubMed:26449471, PubMed:26586190, PubMed:26612684, PubMed:3...

    Polypeptides: Sestrin-2
  8. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    through V<sub>1</sub> and V<sub>2</sub> cellular receptors. … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]

    Products: ./2 ml Konzentrat zur Herstellung einer Infusionslösung, VASOPRESSIN INJECTION USP 20 u/ml
  9. Drug

    XPro1595

    go.drugbank.com/drugs/DB16454
    Investigational

    XPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.

    Synonyms: HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA., SOLUBLE TUMOR NECROSIS FACTOR (1-METHIONINE,31-CYSTEINE,69-VALINE,87-HISTIDINE,101-ALANINE,145-ARGININE) (HUMAN CONSTRUCT XPRO1595), 31-THIOETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL
  10. Drug

    Docaravimab

    go.drugbank.com/drugs/DB17802
    Experimental

    Synonyms: Immunoglobulin g2, anti-(rabies virus strain evelyn-rockitniki-abelseth glycoprotein ectodomain epitope g-iii) (mus musculus monoclonal .gamma.2-chain), disulfide with mus musculus monoclonal .kappa., Immunoglobulin g2b, anti-(rabies virus strain evelyn-rockitniki-abelseth glycoprotein ectodomain epitope g-iii) (mus musculus monoclonal 62-71-3 .gamma.2b-chain), disulfide with mus musculus monoclonal