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Displaying results 4501 - 4510 of 10000 in total
  1. Target

    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

    go.drugbank.com/bio_entities/BE0002192
    TargetHumans

    Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links

    Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2Synonyms: Lysyl hydroxylase 2
  2. Target

    POU domain, class 2, transcription factor 2

    go.drugbank.com/bio_entities/BE0004865
    EnzymeTransporterHumans

    Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addi...

    Polypeptides: POU domain, class 2, transcription factor 2Synonyms: Oct-2, OTF-2
  3. Drug

    Sultamicillin

    go.drugbank.com/drugs/DB12127
    ApprovedWithdrawn

    Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

    Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: NOBECID 375 MG FILM TABLET, 20 ADET, DEVASID 375 MG FILM KAPLI TABLET, 20 ADET
  4. Drug

    Sulodexide

    go.drugbank.com/drugs/DB06271
    ApprovedInvestigationalWithdrawn

    Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

    Products: ANJIOFLUX 600 LRU 2 ML ENJEKTABL COZELTI ICEREN 10 AMPUL, VESSEL DUE F
  5. Drug

    Ferrous succinate

    go.drugbank.com/drugs/DB14489
    ApprovedInvestigational

    Products: FERRLECIT 2
  6. Drug

    Lamotrigine

    go.drugbank.com/drugs/DB00555
    ApprovedInvestigational

    It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
  7. Target

    2-methylisocitrate lyase

    go.drugbank.com/bio_entities/BE0001259
    TargetEscherichia coli (strain K12)

    Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). … Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

    Polypeptides: 2-methylisocitrate lyaseSynonyms: 2-MIC, (2R,3S)-2-methylisocitrate lyase
  8. Target

    2-hydroxymuconate tautomerase

    go.drugbank.com/bio_entities/BE0001410
    TargetPseudomonas putida

    Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.

    Polypeptides: 2-hydroxymuconate tautomerase
  9. Target

    Tryptase beta-2

    go.drugbank.com/bio_entities/BE0001474
    TargetHumans

    Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity

    Polypeptides: Tryptase beta-2Synonyms: Tryptase-2
  10. Target

    Peptide deformylase 2

    go.drugbank.com/bio_entities/BE0001645
    TargetGeobacillus stearothermophilus

    Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity ...

    Polypeptides: Peptide deformylase 2Synonyms: PDF 2, Polypeptide deformylase 2