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Neuronal acetylcholine receptor subunit beta-4
go.drugbank.com/bio_entities/BE0003584TargetHumansComponent of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...
Polypeptides: Neuronal acetylcholine receptor subunit beta-4Interleukin-1 receptor-associated kinase 4
go.drugbank.com/bio_entities/BE0004344TargetHumansSerine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways (PubMed:17878374). Is rapidly recruited by MYD88...
Polypeptides: Interleukin-1 receptor-associated kinase 4Synonyms: IRAK-4Ribosomal protein S6 kinase alpha-4
go.drugbank.com/bio_entities/BE0004614TargetHumansSerine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activati...
Polypeptides: Ribosomal protein S6 kinase alpha-4Synonyms: S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4Serine/threonine-protein kinase PAK 4
go.drugbank.com/bio_entities/BE0009508TargetHumansSerine/threonine-protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell adhesion turnover, cell migration, growth, proliferation or cell survival (PubMed:26598620). Activatio...
Polypeptides: Serine/threonine-protein kinase PAK 4Synonyms: PAK-4, p21-activated kinase 4C-C chemokine receptor type 4
go.drugbank.com/bio_entities/BE0009787TargetHumansHigh affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can func...
Polypeptides: C-C chemokine receptor type 4Synonyms: CCR-4, CC-CKR-4Solute carrier family 13 member 4
go.drugbank.com/bio_entities/BE0010199TransporterHumansSodium:sulfate symporter that mediates sulfate reabsorption in the high endothelial venules (HEV)
Polypeptides: Solute carrier family 13 member 4Short transient receptor potential channel 4
go.drugbank.com/bio_entities/BE0020751TargetHumansForms a receptor-activated non-selective calcium permeant cation channel (PubMed:11042129, PubMed:11713258, PubMed:16144838, PubMed:39478185). Acts as a cell-cell contact-dependent endothelial calcium entry channel (PubMed:19996314). For...
Polypeptides: Short transient receptor potential channel 4Synonyms: hTrp-4, Trp-related protein 4Cholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalVitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation
Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-DCardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z))
smpdb.ca/view/SMP0029734MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
smpdb.ca/view/SMP0220161MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...