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Displaying results 4531 - 4540 of 10000 in total
  1. Target

    Histone deacetylase 2

    go.drugbank.com/bio_entities/BE0002366
    TargetHumans

    (2-hydroxyisobutyryl) acyl groups from lysine residues, leading to protein decrotonylation, delactylation and de-2-hydroxyisobutyrylation, respectively (PubMed:28497810, PubMed:29192674, PubMed:35044827 … In addition to protein deacetylase activity, also acts as a protein-lysine deacylase by recognizing other acyl groups: catalyzes removal of (2E)-butenoyl (crotonyl), lactoyl (lactyl) and 2-hydroxyisobutanoyl

    Polypeptides: Histone deacetylase 2
  2. Target

    Uridine phosphorylase 2

    go.drugbank.com/bio_entities/BE0002457
    EnzymeHumans

    Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (PubMed:12849978, PubMed:2...

    Polypeptides: Uridine phosphorylase 2Synonyms: UPase 2, UrdPase 2
  3. Target

    Phosphoglycerate mutase 2

    go.drugbank.com/bio_entities/BE0004462
    TargetHumans

    Catalyzes the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.

    Polypeptides: Phosphoglycerate mutase 2Synonyms: BPG-dependent PGAM 2
  4. Target

    RuvB-like 2

    go.drugbank.com/bio_entities/BE0009019
    TargetHumans

    Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase act...

    Polypeptides: RuvB-like 2
  5. Target

    Iduronate 2-sulfatase

    go.drugbank.com/bio_entities/BE0009328
    EnzymeTargetHumans

    Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate

    Polypeptides: Iduronate 2-sulfatase
  6. Target

    Deoxyribonuclease-2-alpha

    go.drugbank.com/bio_entities/BE0011359
    TargetHumans

    Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the clearance of nucleic acids generated through apoptosis, hence preventing autoinflammation (PubMed:29259162, PubMed:31775019). Nec...

    Polypeptides: Deoxyribonuclease-2-alpha
  7. Target

    Lysophosphatidylcholine acyltransferase 2

    go.drugbank.com/bio_entities/BE0016122
    TargetEnzymeHumans

    Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor (By similarity). … Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position

    Polypeptides: Lysophosphatidylcholine acyltransferase 2Synonyms: LPCAT-2, LPC acyltransferase 2
  8. Target

    Adenosine deaminase 2

    go.drugbank.com/bio_entities/BE0020559
    EnzymeHumans

    Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surf...

    Polypeptides: Adenosine deaminase 2
  9. Target

    Interleukin-2 receptor

    go.drugbank.com/bio_entities/BE0027978
    TargetHumans

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. … Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.

    Polypeptides: Interleukin-2 receptor subunit alpha, Interleukin-2 receptor subunit betaSynonyms: IL-2-RA, IL-2 receptor subunit gamma
  10. Drug

    Potassium Iodide

    go.drugbank.com/drugs/DB06715
    ApprovedInvestigational

    Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radi...

    Mixtures: Folika-MG, Multi #2Products: YODOFAM JARABE X 120 ML, Kaliumiodid SERB 65 mg Tabletten