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Displaying results 4531 - 4540 of 10000 in total
  1. Target

    Matrix protein 2

    go.drugbank.com/bio_entities/BE0000630
    TargetInfluenza A virus (strain A/Ann Arbor/6/1960 H2N2)

    Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome trigge...

    Polypeptides: Matrix protein 2
  2. Target

    Arginase-2, mitochondrial

    go.drugbank.com/bio_entities/BE0000758
    TargetHumans

    Since NOS is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase-2 plays a role in both male and female sexual arousal (PubMed:12859189)

    Polypeptides: Arginase-2, mitochondrial
  3. Target

    Heparin cofactor 2

    go.drugbank.com/bio_entities/BE0000775
    TargetHumans

    Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but i...

    Polypeptides: Heparin cofactor 2Synonyms: Protease inhibitor leuserpin-2
  4. Target

    Glutathione peroxidase 2

    go.drugbank.com/bio_entities/BE0000817
    TargetHumans

    Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis (PubMed:36608588, PubMed:8428933). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert...

    Polypeptides: Glutathione peroxidase 2Synonyms: GPx-2, GPRP-2
  5. Target

    Alpha-2-macroglobulin

    go.drugbank.com/bio_entities/BE0000910
    TargetCarrierHumans

    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves...

    Polypeptides: Alpha-2-macroglobulinSynonyms: Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
  6. Target

    Inositol monophosphatase 2

    go.drugbank.com/bio_entities/BE0000983
    TargetHumans

    Phosphatase that can use myo-inositol monophosphates, myo-inositol 1,4-diphosphate, scyllo-inositol-1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate and 2'-AMP as substrates in vitro (PubMed

    Polypeptides: Inositol monophosphatase 2Synonyms: IMP 2, IMPase 2
  7. Target

    Neuroendocrine convertase 2

    go.drugbank.com/bio_entities/BE0002124
    EnzymeHumans

    Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues (PubMed:28719828, PubMed:7626024, PubMed:8879041, PubMed:9287128). Responsible for ...

    Polypeptides: Neuroendocrine convertase 2Synonyms: NEC 2, KEX2-like endoprotease 2
  8. Target

    P2Y purinoceptor 2

    go.drugbank.com/bio_entities/BE0002401
    TargetHumans

    The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP

    Polypeptides: P2Y purinoceptor 2
  9. Target

    2-methylcitrate synthase

    go.drugbank.com/bio_entities/BE0002690
    TargetAntarctic bacterium DS2-3R

    Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. … Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route).

    Polypeptides: 2-methylcitrate synthaseSynonyms: 2-MCS, (2S,3S)-2-methylcitrate synthase
  10. Target

    Nucleoside 2-deoxyribosyltransferase

    go.drugbank.com/bio_entities/BE0003329
    TargetTrypanosoma brucei brucei (strain 927/4 GUTat10.1)

    Polypeptides: Nucleoside 2-deoxyribosyltransferase