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Displaying results 4551 - 4560 of 10000 in total
  1. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3)

    Polypeptides: Relaxin receptor 2Synonyms: Relaxin family peptide receptor 2
  2. Target

    Protein argonaute-2

    go.drugbank.com/bio_entities/BE0020979
    TargetHumans

    Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide R...

    Polypeptides: Protein argonaute-2Synonyms: eIF2C 2, eIF-2C 2
  3. Target

    Carbonic anhydrase 2

    go.drugbank.com/bio_entities/BE0000322
    TargetEnzymeCarrierHumans

    Catalyzes the reversible hydration of carbon dioxide (PubMed:11327835, PubMed:11802772, PubMed:11831900, PubMed:12056894, PubMed:12171926, PubMed:1336460, PubMed:14736236, PubMed:15300855, PubMed:15453828, PubMed:15667203, PubMed:1586543...

    Polypeptides: Carbonic anhydrase 2
  4. Target

    Monocarboxylate transporter 2

    go.drugbank.com/bio_entities/BE0000440
    TargetTransporterHumans

    Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate (PubMed:32415067, PubMed...

    Polypeptides: Monocarboxylate transporter 2Synonyms: MCT 2
  5. Target

    Antizyme inhibitor 2

    go.drugbank.com/bio_entities/BE0000448
    TargetHumans

    Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 a...

    Polypeptides: Antizyme inhibitor 2
  6. Target

    Retinal dehydrogenase 2

    go.drugbank.com/bio_entities/BE0000513
    TargetHumans

    Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (...

    Polypeptides: Retinal dehydrogenase 2Synonyms: RALDH 2, Retinaldehyde-specific dehydrogenase type 2
  7. Target

    Glutamate carboxypeptidase 2

    go.drugbank.com/bio_entities/BE0000568
    TargetHumans

    Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory n...

    Polypeptides: Glutamate carboxypeptidase 2
  8. Target

    Heme oxygenase 2

    go.drugbank.com/bio_entities/BE0000587
    TargetHumans

    Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron

    Polypeptides: Heme oxygenase 2Synonyms: HO-2
  9. Target

    Glutamate decarboxylase 2

    go.drugbank.com/bio_entities/BE0000602
    TargetHumans

    Catalyzes the production of GABA

    Polypeptides: Glutamate decarboxylase 2
  10. Target

    Serine palmitoyltransferase 2

    go.drugbank.com/bio_entities/BE0000660
    TargetHumans

    Component of the serine palmitoyltransferase multisubunit enzyme (SPT) that catalyzes the initial and rate-limiting step in sphingolipid biosynthesis by condensing L-serine and activated acyl-CoA (most commonly palmitoyl-CoA) to form lon...

    Polypeptides: Serine palmitoyltransferase 2Synonyms: LCB 2, SPT 2