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Displaying results 4611 - 4620 of 10000 in total
  1. Drug

    Guselkumab

    go.drugbank.com/drugs/DB11834
    ApprovedInvestigational

    Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. … IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357].

    Products: TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET, TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  2. Drug

    Magrolimab

    go.drugbank.com/drugs/DB16225
    Investigational

    Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).

    Synonyms: )) (8.8.10) (1-117)-homo sapiens ighg4*01 (ch1 (118-2, Immunoglobulin g4-kappa, anti-(homo sapiens cd47 (integrin associated protein, iap, mer6, oa3)), monoclonal antibodygamma4 heavy chain (1-444) (vh (homo sapiens ighv1-3*01 (87.8%)-(ighd)-ighj4*01 (100%
  3. Drug

    Goflikicept

    go.drugbank.com/drugs/DB16396
    Investigational

    Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe … Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).

    Categories: Experimental Unapproved Treatments for COVID-19Synonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein
  4. Indication

    Essential Thrombocythemia (ET)

    go.drugbank.com/conditions/DBCOND0048758
    Drugs: Busulfan · Hydroxyurea
    Synonyms: ET (Essential Thrombocythemia), Essential Thrombocythemia (ET)
  5. Drug

    VL-2397

    go.drugbank.com/drugs/DB17796
    Investigational

    Synonyms: Cyclo(l-asparaginyl-l-leucyl-d-phenylalanyl-n5-acetyl-n5-hydroxy-l-ornithyl-n5-acetyl-n5-hydroxy-l-ornithyl-n5-acetyl-n5-hydroxy-l-ornithyl), aluminum salt (1:1), Cyclo(-asn-leu-d-phe-al((n5-acetyl-n5-hydroxy-orn)-(n5-acetyl-n5-hydroxy-orn)-(n5-hydroxy-orn))-) . al(iii)
  6. Drug

    LP-184

    go.drugbank.com/drugs/DB18215
    Investigational

    Synonyms: (R)-1-HYDROXY-1-((6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXO-6',7'-DIHYDROSPIRO(CYCLOPROPANE-1,5'-INDEN)-3'-YL)METHYL)UREA, N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)-3'-YL)METHYL)-N-HYDROXYUREA
  7. Drug

    Nelarabine

    go.drugbank.com/drugs/DB01280
    ApprovedInvestigational

    [A2331,AA2334,A2335] Results from 2 phase 2 studies on adult and pediatric T-ALL/T-LBL indicated that nelarabine can yield a 13% complete response (CR) rate in pediatric patients and 18% in adult patients … [A2332] Due to the rarity of these T-cell malignancies, nelarabine was first granted orphan drug status and a fast-track designation by the FDA to address the unmet therapeutic needs of these cancers.

    Synonyms: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purineProducts: NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 1 ADET, NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 6 ADET
  8. Pathway

    Acylcarnitine (4Z,7Z,10Z)-12-[(1S,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxypent-1-en-1-yl]-5-oxocyclopentyl]dodeca-4,7,10-trienoylcarnitine

    smpdb.ca/view/SMP0123557
    Metabolic

    12-[(1S,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxypent-1-en-1-yl]-5-oxocyclopentyl]dodeca-4,7,10-trienoylcarnitine. … (4Z,7Z,10Z)-12-[(1S,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxypent-1-en-1-yl]-5-oxocyclopentyl]dodeca-4,7,10-trienoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Acetyl-CoA carboxylase 1
  9. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.

    Mixtures: Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 5) - Rose, Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 5) - BeigeCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    (4R)-limonene 1α,2α-epoxide

    go.drugbank.com/drugs/DB02924
    Experimental

    Synonyms: 1α,2α-epoxy-4βH-p-menth-8-ene, D-limonene 1,2-epoxide