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Displaying results 461 - 470 of 9613 in total
  1. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204134] When compared to [hydrochlorothiazide] (another commonly prescribed diuretic), indapamide has been shown to be superior at lowering systolic blood pressure, reducing left ventricular mass index … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive

    Mixtures: COVERSYL PLUS Tablet 10mg/2.5mg, COVERSYL PLUS 10MG/2.5MG FILM-COATED TABLETProducts: PMS-indapamide, INDAPAMID - CT 2.5 MG HART
  2. Drug

    Pembrolizumab

    go.drugbank.com/drugs/DB09037
    ApprovedInvestigational

    [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.

    Products: KEYTRUDA SOLUTION FOR INFUSION 25MG/ML, Keytruda 100mg Solution for Infusion
  3. Drug

    Metolazone

    go.drugbank.com/drugs/DB00524
    ApprovedInvestigational

    It also tends to lower blood pressure and increase potassium loss.

    Products: Zaroxolyn Tab 10mg
  4. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix.

    Products: MITONCO 10mg powder for solution for injection/infusion or intravesical, Mutamycin Inj 20mg/vial
  5. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    It is available OTC in Europe.

    Products: FLUVERMAL SUSPENSION 20MG/ML, HELMIN EX SUSPENSION 100MG/5ML
  6. Drug

    Exemestane

    go.drugbank.com/drugs/DB00990
    ApprovedInvestigational

    It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.

    Products: EXEMESTANE EG, TABLET 25MG
  7. Indication

    Essential Thrombocythemia (ET)

    go.drugbank.com/conditions/DBCOND0048758
    Drugs: Busulfan · Hydroxyurea · Pacritinib
    Synonyms: ET (Essential Thrombocythemia), Essential Thrombocythemia (ET)
  8. Drug

    Protriptyline

    go.drugbank.com/drugs/DB00344
    Approved

    Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In...

    Products: Triptil Tab 10mg
  9. Drug

    Teriflunomide

    go.drugbank.com/drugs/DB08880
    ApprovedInvestigational

    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.

    Products: AUBAGIO FILM-COATED TABLETS 14mg, AUBAGIO 14mg Film-coated Tablets
  10. Drug

    Raltegravir

    go.drugbank.com/drugs/DB06817
    ApprovedInvestigational

    It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.

    Products: ISENTRESS® TABLETAS MASTICABLES 100MG, 400MG TABLET