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Zidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: COMBİVİR 150 MG/300 MG FİLM KAPLI TABLET, LAMIVUDINA 150 MG + ZIDOVUDINA 300 MG + NEVIRAPINA 200 MG TABLETAS CUBIERTASCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Synonyms: 5 FU, 5-FUMixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)Sodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Mixtures: AMINOMIX 2 NOVUM 1000 ML, AMINOMIX 2 NOVUM 1500 MLProducts: DROSER 180 MG / 20 ML BURUN DAMLASI, ÇÖZELTİ, 20 ML, CLORURO DE SODIO 9 MG / MLFluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnFluticasone is a synthetic glucocorticoid available as 2 esters, [DB08906] and [DB00588][F4355,F4358,F4361,F4364][FDA Label].
Mixtures: PAVTIDE DISKUS 100 MCG INHALASYON ICIN TOZ, 60 DOZ, PAVTIDE DISKUS 250 MCG INHALASYON ICIN TOZ, 60 DOZCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAcetohydroxamic acid
go.drugbank.com/drugs/DB00551ApprovedInvestigationalAcetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease.
Synonyms: N-Hydroxyacetamide, N-AcetylhydroxylamineProducts: QUINOPRON ® INYECTABLE 200 MG, CIPROFLOXACINO 100 MG/10 ML INYECTABLETerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigationalTerlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor.
Products: HAEMOPRESSIN® 1 MG, GLYPRESSIN ® 1 MGDurvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigationalDurvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. … [A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI® 50 MG/ML CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN, IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: XENABI FORTE 120 MG KAPSUL, 21 ADET, FINOBES ® 120 MG.Bevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigational[A193272,A193275,L12648] Avastin was subsequently approved by Health Canada on March 24, 2010 and by the European Commission on April 21, 2021. … [A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A.
Synonyms: 贝伐珠单抗International brands: 安倍斯, 安维汀Carboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalIt is added in food products as a viscosity modifier or thickener and emulsifier. … Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.
Mixtures: OPTIVE ®, OPTIVE ®Categories: Compounds used in a research, industrial, or household setting