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Displaying results 4791 - 4800 of 10000 in total
  1. Target

    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

    go.drugbank.com/bio_entities/BE0001661
    TargetEscherichia coli (strain K12)

    Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  2. Target

    2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

    go.drugbank.com/bio_entities/BE0001839
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
  3. Target

    G protein-activated inward rectifier potassium channel 4

    go.drugbank.com/bio_entities/BE0002218
    TargetHumans

    Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.

    Polypeptides: G protein-activated inward rectifier potassium channel 4Synonyms: GIRK-4, IRK-4
  4. Target

    Potassium voltage-gated channel subfamily KQT member 4

    go.drugbank.com/bio_entities/BE0002399
    TargetHumans

    KCNQ4/Kv7.4 channel is composed of 4 pore-forming subunits assembled as tetramers (PubMed:34767770). … The channel conducts a slowly activating and deactivating current (PubMed:10025409, PubMed:11245603). Current often shows some inward rectification at positive potentials (PubMed:10025409).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 4Synonyms: KQT-like 4
  5. Target

    UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase

    go.drugbank.com/bio_entities/BE0002630
    TargetPseudomonas aeruginosa

    Polypeptides: UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimeraseSynonyms: UDP-GlcNAcA 4-epimerase
  6. Target

    C-type lectin domain family 4 member E

    go.drugbank.com/bio_entities/BE0009096
    TargetHumans

    Interacts with signaling adapter Fc receptor gamma chain/FCER1G to form a functional complex in myeloid cells (By similarity). … The PAMPs notably include mycobacterial trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid with potent adjuvant immunomodulatory functions (PubMed:23602766, PubMed:24101491).

    Polypeptides: C-type lectin domain family 4 member E
  7. Target

    C-type lectin domain family 4 member C

    go.drugbank.com/bio_entities/BE0010522
    TargetHumans

    Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed:21880719, PubMed:25995448). … May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed:11748283)

    Polypeptides: C-type lectin domain family 4 member C
  8. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4

    go.drugbank.com/conditions/DBCOND0093777
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4
  9. Drug

    Etelcalcetide

    go.drugbank.com/drugs/DB12865
    ApprovedInvestigational

    Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.

    Products: PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET
  10. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.

    Synonyms: PVP-IMixtures: P-Care MG, Physicians EZ Use M-pred