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Gatifloxacin
go.drugbank.com/drugs/DB01044ApprovedInvestigationalWithdrawnIt is also available as eye drops under the brand name Zymar® marketed by Allergan. … It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsSelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalThe novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform neurofibromas (PN
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalNSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole … sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort, including pain, burning or pricking, or a tingling sensation after instillation into the cul‐de‐sac
Mixtures: SATOGESIC GEL, BEVODINIX-GELCategories: P-glycoprotein inhibitors, P-glycoprotein substratesMeclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigational[L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesPectin
go.drugbank.com/drugs/DB11158ApprovedInvestigationalVet approvedPectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin...
Mixtures: LEOLIN-P®, Donnagel-PG LiqHydroxypropyl cellulose
go.drugbank.com/drugs/DB00840ApprovedHydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artifici...
International brands: A-GelRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...
Mixtures: Daily Energy Brand B-complex, Doctor's Choice Brand for MenLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigationalLansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: LANSOPRAZOLO MYLAN GENERICS, LANSOPRAZOLO MYLAN GENERICS ITALIAHalcinonide
go.drugbank.com/drugs/DB06786ApprovedWithdrawnHalcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors