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Daclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnThe same dosing regimen can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis. … According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b patients with or without cirrhosis as second-line
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60Etidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901] … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].
Synonyms: 1-Hydroxy-1,1-diphosphonoethane, (1-Hydroxyethylene)diphosphonic acidProducts: DIDRONAT 200 MG TABLET, 60 ADET, DIDRONAT 400 MG TABLET, 30 ADETRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedIt occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.
Mixtures: B Plus C 300 mg, COMPLEJO B EN KOLA GRANULADACategories: Vitamin B Complex, Heterocyclic Compounds, 2-RingAluminum hydroxide
go.drugbank.com/drugs/DB06723ApprovedInvestigationalAluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Mixtures: HIDROXDO DE ALUMINIO 4% + HIDROXDO DE MAGNESIO 4% + SIMETICONA 0.4% SUSPENSION, HIDROXIDO DE ALUMINIO 4% + HIDROXIDO DE MAGNESIO 4% + SIMETICONA 0.4% SUSPENSIONProducts: GALAC H, GASTROVAN®Indocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalThe chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, … Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: VERDYE 5 mg/ml Injektionszubereitung, ไดแอกโนกรีน(R) ชนิดฉีด 25 มิลลิกรัมEptinezumab
go.drugbank.com/drugs/DB14040ApprovedInvestigationalEptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals. … [F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of migraine headaches in adults.[L12318]
Products: Vyepti® 100 mg/mL concentrate for solution for infusion, VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/MLSodium fluoride
go.drugbank.com/drugs/DB09325ApprovedInvestigationalSodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care.
Mixtures: PREVENT 2 EN 1, 4 PackCategories: Compounds used in a research, industrial, or household settingTezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigational[A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes. … [A243764, A243769, A243774] Tezepelumab is a human monoclonal IgG2λ antibody directed against TSLP produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Synonyms: AMG 157, AMG-157Products: Tezspire 210 mg/1,91 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), TEZSPIRE®Acylcarnitine 4-ethoxy-4-oxobutanoylcarnitine
smpdb.ca/view/SMP0123476MetabolicOnce inside the cell it undergoes a reaction to form an acyl-CoA derivative called 4-ethoxy-4-oxobutanoyl-CoA. … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor.
Mixtures: CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET, CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLETCategories: Heterocyclic Compounds, 2-Ring, Drugs Used in Addictive Disorders