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Somapacitan
go.drugbank.com/drugs/DB15093ApprovedInvestigational[A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666] … Somapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), Sogroya® 10 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalInduction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.
Synonyms: e-ATG, h-ATGCategories: Immunoglobulin G, Increased T Lymphocyte DestructionRisankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigationalRisankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23).
Categories: Interleukin-23 Antagonist, Interleukin-23 Subunit p19Products: Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETPanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab was granted FDA approval on 27 September 2006.[L17663] … Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Products: VECTIBIX® 20 MG/ ML, VECTIBIX 20 MG/ML 20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET17-beta-hydroxysteroid dehydrogenase type 2
go.drugbank.com/bio_entities/BE0000006TargetEnzymeHumansCatalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these ste...
Polypeptides: 17-beta-hydroxysteroid dehydrogenase type 2Synonyms: 17-beta-HSD 2, Estradiol 17-beta-dehydrogenase 211-beta-hydroxysteroid dehydrogenase type 2
go.drugbank.com/bio_entities/BE0000131TargetEnzymeHumanshydroxycholesterol in vitro (PubMed:30902677). 7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as a ligand for the G protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2
Polypeptides: 11-beta-hydroxysteroid dehydrogenase type 2Synonyms: Corticosteroid 11-beta-dehydrogenase isozyme 23-hydroxyacyl-CoA dehydrogenase type-2
go.drugbank.com/bio_entities/BE0000317TargetEnzymeHumansCatalyzes the oxidation of 3-hydroxy-2-methylbutanoyl-CoA into 2-methyl-3-oxobutanoyl-CoA, a step in isoleucine degradation pathway (PubMed:18996107, PubMed:19706438, PubMed:20077426). … Acts as 3-hydroxy-2-methylbutyryl-CoA dehydrogenase in branched-chain amino acid catabolic pathway.
Polypeptides: 3-hydroxyacyl-CoA dehydrogenase type-2Synonyms: Mitochondrial RNase P protein 2, 2-methyl-3-hydroxybutyryl-CoA dehydrogenaseG protein-coupled receptor kinase 2
go.drugbank.com/bio_entities/BE0000341TargetHumansSpecifically phosphorylates the activated forms of G protein-coupled receptors (PubMed:14976224, PubMed:16179383, PubMed:19306925, PubMed:19715378, PubMed:21799898, PubMed:23077507, PubMed:30284927, PubMed:33859231, PubMed:39138140, PubM...
Polypeptides: G protein-coupled receptor kinase 2Solute carrier family 13 member 2
go.drugbank.com/bio_entities/BE0000447TransporterHumansLow-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small
Polypeptides: Solute carrier family 13 member 2Receptor tyrosine-protein kinase erbB-2
go.drugbank.com/bio_entities/BE0000511TargetEnzymeHumansProtein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with i...
Polypeptides: Receptor tyrosine-protein kinase erbB-2Synonyms: Proto-oncogene c-ErbB-2