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Trimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine, 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepineFerric ammonium citrate
go.drugbank.com/drugs/DB09501ApprovedWithdrawnProducts: FOLITON 250 MG/5 ML ŞURUP, 120 ML, KİNAMALT SİROP, 250 GMagnesium oxide
go.drugbank.com/drugs/DB01377ApprovedInvestigationalMagnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Mixtures: SELDIYET GRANUL, 50 GR, DIMAG 365 MG TEK KULLANIMLIK TOZ ICEREN SAŞE, 20 ADETProducts: Magnesium 250 mg, MAGNEZI KALSINE 100 G TOZ, 100 GAntihemophilic factor, human recombinant
go.drugbank.com/drugs/DB00025ApprovedInvestigationalHuman recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Mixtures: FANHDI 250 U.I., FANHDI 500 U.I.Categories: Hemophilia AIbrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November 2014.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneBicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalIt is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsProducts: BICAN ® 50 MG TABLETAS, CASODEX® 50 MG TABLETASDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: RABELIS PLUS 20/30 MG MR KAPSUL, 30 ADET, RABELIS PLUS 20/10 MG KAPSUL, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesBethanechol
go.drugbank.com/drugs/DB01019ApprovedBethanechol is a synthetic ester that was initially synthesized in 1935. … An advantage of bethanechol is that in contrast to acetylcholine, bethanechol is not degraded by cholinesterase allowing its effects to be longer-lasting.[L32539]
Synonyms: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium, carbamyl-β-methylcholineProducts: Myocholine - Glenwood Tabletten 25 mg, Myocholine - Glenwood Tabletten 10 mgAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalallergic rhinitis in patients 6 years of age and older. … [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal
Mixtures: DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 23 G, DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 6,4 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesDiosmin
go.drugbank.com/drugs/DB08995ApprovedInvestigationalDiosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile.[A232890,T840,L33040] … Chronic venous insufficiency is a common condition the western population.
Mixtures: VENOMAX ® 500 MG TABLETAS, DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADETCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 CYP2E1 Inhibitors