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Displaying results 5301 - 5310 of 10000 in total
  1. Target

    5-methyltetrahydrofolate--homocysteine S-methyltransferase

    go.drugbank.com/bio_entities/BE0002812
    TargetMoorella thermoacetica (strain ATCC 39073)

    Polypeptides: 5-methyltetrahydrofolate--homocysteine S-methyltransferase
  2. Target

    Ribose-5-phosphate isomerase B

    go.drugbank.com/bio_entities/BE0002944
    TargetMycobacterium tuberculosis

    Catalyzes the interconversion of ribulose-5-P and ribose-5-P. It has not isomerase activity towards D-allose 6-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase BFunction: ribose-5-phosphate isomerase activity
  3. Target

    Pyrroline-5-carboxylate reductase 3

    go.drugbank.com/bio_entities/BE0004615
    TargetHumans

    Proline is synthesized from either glutamate or ornithine; both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs) (PubMed:23024808). … Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H (PubMed:23024808, PubMed:36414121).

    Polypeptides: Pyrroline-5-carboxylate reductase 3Synonyms: Pyrroline-5-carboxylate reductase-like protein
  4. Target

    DAN domain family member 5

    go.drugbank.com/bio_entities/BE0005538
    TargetHumans

    Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development (By similarity). Antagonist of BMP and TGF-beta signaling (PubMed:33587337). Independently of its r...

    Polypeptides: DAN domain family member 5Synonyms: Cysteine knot superfamily 1, BMP antagonist 3
  5. Target

    Ephrin type-A receptor 5

    go.drugbank.com/bio_entities/BE0005587
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the rece...

    Polypeptides: Ephrin type-A receptor 5Synonyms: EHK-1, EPH homology kinase 1
  6. Target

    DNA (cytosine-5)-methyltransferase 3B

    go.drugbank.com/bio_entities/BE0010009
    TargetHumans

    Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Functions as a transcriptional corepressor by associating with ZHX1.

    Polypeptides: DNA (cytosine-5)-methyltransferase 3BFunction: DNA (cytosine-5-)-methyltransferase activity
  7. Target

    3',5'-cyclic-nucleotide phosphodiesterase

    go.drugbank.com/bio_entities/BE0010168
    TargetRabbit

    Polypeptides: 3',5'-cyclic-nucleotide phosphodiesteraseFunction: 3',5'-cyclic-AMP phosphodiesterase activity
  8. Target

    5'-AMP-activated protein kinase

    go.drugbank.com/bio_entities/BE0011011
    TargetRat

    Promotes lipolysis of lipid droplets by mediating phosphorylation of isoform 1 of CHKA (CHKalpha2) (By similarity). … Promotes lipolysis of lipid droplets by mediating phosphorylation of isoform 1 of CHKA (CHKalpha2) (By similarity).

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1Synonyms: 5'-AMP-activated protein kinase 40 kDa subunit, AMPK subunit alpha-1
  9. Target

    Pyrroline-5-carboxylate reductase 2

    go.drugbank.com/bio_entities/BE0000728
    TargetHumans

    Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:23024808, PubMed:2722838, PubMed:6894153

    Polypeptides: Pyrroline-5-carboxylate reductase 2Function: pyrroline-5-carboxylate reductase activity
  10. Target

    Glutamate receptor ionotropic, kainate 5

    go.drugbank.com/bio_entities/BE0000828
    TargetHumans

    Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in...

    Polypeptides: Glutamate receptor ionotropic, kainate 5