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Displaying results 531 - 540 of 10000 in total
  1. Target

    Blasticidin-S deaminase

    go.drugbank.com/bio_entities/BE0003364
    TargetAspergillus terreus

    Catalyzes the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.

    Polypeptides: Blasticidin-S deaminaseFunction: blasticidin-S deaminase activity
  2. Target

    Glutathione S-transferase

    go.drugbank.com/bio_entities/BE0004124
    TargetBurkholderia xenovorans (strain LB400)

    Polypeptides: Glutathione S-transferaseSynonyms: Glutathione S-transferase (BphK)
  3. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0009188
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

    Polypeptides: S-adenosylmethionine synthase
  4. Target

    Thiopurine S-methyltransferase

    go.drugbank.com/bio_entities/BE0000987
    EnzymeTargetHumans

    Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine

    Polypeptides: Thiopurine S-methyltransferaseFunction: S-adenosyl-L-methionine binding
  5. Target

    S-ribosylhomocysteine lyase

    go.drugbank.com/bio_entities/BE0001497
    TargetBacillus subtilis (strain 168)

    Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

    Polypeptides: S-ribosylhomocysteine lyase
  6. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0001499
    TargetShigella flexneri

    Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.

    Polypeptides: S-adenosylmethionine synthase
  7. Target

    Glutathione S-transferase

    go.drugbank.com/bio_entities/BE0002659
    TargetEnzymePlasmodium falciparum

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).

    Polypeptides: Glutathione S-transferase
  8. Drug

    Acazicolcept

    go.drugbank.com/drugs/DB18410
    Investigational

    Synonyms: (133-363) VARIANT (C137>S, L151>A, L152>E, G154>A,, .1-CHAIN C REGION VARIANT C-TERMINAL FRAGMENT), DIMER
  9. Drug

    JNJ-55308942

    go.drugbank.com/drugs/DB19110
    Investigational

    JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

    Synonyms: (S)-(3-Fluoro-2-(trifluoromethyl)pyridin-4-yl)(1-(5-fluoropyrimidin-2-yl)-6-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)methanone, ((6S)-1-(5-FLUORO-2-PYRIMIDINYL)-1,4,6,7-TETRAHYDRO-6-METHYL-5H-1,2,3-TRIAZOLO(4,5-C)PYRIDIN-5-YL)(3-FLUORO-2-(TRIFLUOROMETHYL)-4-PYRIDINYL)METHANONECategories: Heterocyclic Compounds, 1-Ring
  10. Target

    Glutathione S-transferase A4

    go.drugbank.com/bio_entities/BE0000811
    TargetHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE)

    Polypeptides: Glutathione S-transferase A4Synonyms: Glutathione S-transferase A4-4