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Displaying results 5431 - 5440 of 10000 in total
  1. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0125788
    Disease

    A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs and symptoms include night blindness, poor adaptation to darkness, dry skin and hair. … Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them.

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  2. Drug

    Rivastigmine

    go.drugbank.com/drugs/DB00989
    ApprovedInvestigational

    Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
  3. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0000336
    Disease

    A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs and symptoms include night blindness, poor adaptation to darkness, dry skin and hair. … Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them.

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  4. Indication

    Albuminuria

    go.drugbank.com/conditions/DBCOND0001408
    Drugs: Azilsartan medoxomil
    Synonyms: Abnormal presence of protein in urine
  5. Indication

    Pyelonephritis

    go.drugbank.com/conditions/DBCOND0014040
    Drugs: Cefepime · Cefiderocol · Cilastatin · Doripenem · Escherichia coli · Imipenem +6 more
    Synonyms: Renal tubulo-interstitial disorders in diseases classified elsewhere (disorder)
  6. Target

    ATP-dependent 6-phosphofructokinase, muscle type

    go.drugbank.com/bio_entities/BE0012586
    TargetHumans

    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

    Synonyms: PFK-A, 6-phosphofructokinase type A
  7. Drug

    Azathioprine

    go.drugbank.com/drugs/DB00993
    ApprovedInvestigational

    Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
  8. Target

    Phospholipase A1

    go.drugbank.com/bio_entities/BE0002041
    TargetEscherichia coli (strain K12)

    Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins.

    Synonyms: DR-phospholipase A, Outer membrane phospholipase A
  9. Drug

    CP-12

    go.drugbank.com/drugs/DB18169
    Investigational

    Synonyms: CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK), PROLYL-L-SERYL-L-HISTIDYL-L-ISOLEUCYL-L-SERYL-L-LYSYL-L-TYROSYL-L-ISOLEUCYL-L-LEUCYL- L-ARGINYL-L-TRYPTOPHANYL-L-ARGINYL-L-PROLYL-L-LYSYL), CYCLO (1-14)
  10. Target

    Interferon alpha-2

    go.drugbank.com/bio_entities/BE0003450
    TargetHumans

    Produced by macrophages, IFN-alpha have antiviral activities

    Synonyms: LeIF A, Interferon alpha-A