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Displaying results 5451 - 5460 of 10000 in total
  1. Target

    Adenosine 5'-monophosphoramidase HINT1

    go.drugbank.com/bio_entities/BE0001473
    TargetEnzymeHumans

    Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide (PubMed:30772266). … Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate) (PubMed:15703176, PubMed:16835243).

    Polypeptides: Adenosine 5'-monophosphoramidase HINT1Function: adenosine 5'-monophosphoramidase activity
  2. Target

    Pyridoxine 5'-phosphate synthase

    go.drugbank.com/bio_entities/BE0001540
    TargetEscherichia coli (strain K12)

    Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine … 5'-phosphate (PNP) and inorganic phosphate.

    Polypeptides: Pyridoxine 5'-phosphate synthase
  3. Target

    Bis(5'-adenosyl)-triphosphatase

    go.drugbank.com/bio_entities/BE0001687
    TargetHumans

    form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake (PubMed:12574506, PubMed:19622739). … Exhibits adenylylsulfate-ammonia adenylyltransferase, catalyzing the ammonolysis of adenosine 5'-phosphosulfate resulting in the formation of adenosine 5'-phosphoramidate (PubMed:26181368).

    Polypeptides: Bis(5'-adenosyl)-triphosphataseSynonyms: Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Adenosine 5'-monophosphoramidase FHIT
  4. Target

    5-formyltetrahydrofolate cyclo-ligase

    go.drugbank.com/bio_entities/BE0001906
    TargetMycoplasma pneumoniae (strain ATCC 29342 / M129)

    Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.

    Polypeptides: 5-formyltetrahydrofolate cyclo-ligaseFunction: 5-formyltetrahydrofolate cyclo-ligase activity
  5. Target

    Adenylate cyclase type 5

    go.drugbank.com/bio_entities/BE0003733
    TargetHumans

    Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (PubMed:24740569)

    Polypeptides: Adenylate cyclase type 5Synonyms: Adenylyl cyclase 5, ATP pyrophosphate-lyase 5
  6. Target

    Ribose-5-phosphate isomerase

    go.drugbank.com/bio_entities/BE0004438
    TargetHumans

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway

    Polypeptides: Ribose-5-phosphate isomerase
  7. Target

    Uridine 5'-monophosphate synthase

    go.drugbank.com/bio_entities/BE0004473
    TargetEnzymeHumans

    -5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP) … Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine

    Polypeptides: Uridine 5'-monophosphate synthase
  8. Target

    5-hydroxytryptamine receptor 1

    go.drugbank.com/bio_entities/BE0004958
    TargetHumans

    proteins and mediates inhibitory neurotransmission: signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+ … Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism (PubMed:18476671, PubMed:20363322, PubMed:20945968).

    Polypeptides: 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1BSynonyms: 5-HT1A, 5-HT-1A
  9. Target

    5-hydroxytryptamine receptor 3C

    go.drugbank.com/bio_entities/BE0009584
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3CSynonyms: 5-HT3C, 5-HT3-C
  10. Target

    5-hydroxytryptamine 3 receptor

    go.drugbank.com/bio_entities/BE0009860
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons … Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3BSynonyms: 5-HT-3, 5-HT3A