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S-ribosylhomocysteine lyase
go.drugbank.com/bio_entities/BE0001462TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Polypeptides: S-ribosylhomocysteine lyaseS-formylglutathione hydrolase
go.drugbank.com/bio_entities/BE0002283TargetEnzymeHumansSerine hydrolase involved in the detoxification of formaldehyde
Polypeptides: S-formylglutathione hydrolase(S)-mandelate dehydrogenase
go.drugbank.com/bio_entities/BE0003028TargetEnzymePseudomonas putidaCatalyzes the dehydrogenation of (S)-mandelate to phenylglyoxylate (benzoylformate) (PubMed:10493804, PubMed:19465768).
Polypeptides: (S)-mandelate dehydrogenaseFunction: (S)-mandelate dehydrogenase activityBlasticidin-S deaminase
go.drugbank.com/bio_entities/BE0003364TargetAspergillus terreusCatalyzes the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.
Polypeptides: Blasticidin-S deaminaseFunction: blasticidin-S deaminase activityGlutathione S-transferase
go.drugbank.com/bio_entities/BE0004124TargetBurkholderia xenovorans (strain LB400)Polypeptides: Glutathione S-transferaseSynonyms: Glutathione S-transferase (BphK)S-adenosylmethionine synthase
go.drugbank.com/bio_entities/BE0009188TargetPlasmodium falciparum (isolate 3D7)Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
Polypeptides: S-adenosylmethionine synthaseThiopurine S-methyltransferase
go.drugbank.com/bio_entities/BE0000987EnzymeTargetHumansCatalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine
Polypeptides: Thiopurine S-methyltransferaseFunction: S-adenosyl-L-methionine bindingS-ribosylhomocysteine lyase
go.drugbank.com/bio_entities/BE0001497TargetBacillus subtilis (strain 168)Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
Polypeptides: S-ribosylhomocysteine lyaseS-adenosylmethionine synthase
go.drugbank.com/bio_entities/BE0001499TargetShigella flexneriCatalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.
Polypeptides: S-adenosylmethionine synthaseGlutathione S-transferase
go.drugbank.com/bio_entities/BE0002659TargetEnzymePlasmodium falciparumConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).
Polypeptides: Glutathione S-transferase