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Displaying results 551 - 560 of 10000 in total
  1. Target

    O-GlcNAcase NagJ

    go.drugbank.com/bio_entities/BE0003351
    TargetClostridium perfringens (strain 13 / Type A)

    Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro). … Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals.

    Polypeptides: O-GlcNAcase NagJFunction: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
  2. Target

    Acetylserotonin O-methyltransferase

    go.drugbank.com/bio_entities/BE0003553
    EnzymeHumans

    Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine)

    Polypeptides: Acetylserotonin O-methyltransferaseSynonyms: Hydroxyindole O-methyltransferase
  3. Target

    O-GlcNAcase BT_4395

    go.drugbank.com/bio_entities/BE0004258
    TargetBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

    Can hydrolyze the glycosidic link of O-GlcNAcylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).

    Polypeptides: O-GlcNAcase BT_4395Function: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
  4. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0004273
    TargetThermobifida fusca (strain YX)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substra...

    Polypeptides: o-succinylbenzoate synthaseSynonyms: o-succinylbenzoic acid synthase
  5. Target

    Protein O-GlcNAcase

    go.drugbank.com/bio_entities/BE0005827
    TargetHumans

    Cleaves GlcNAc but not GalNAc from O-glycosylated proteins (PubMed:11148210, PubMed:11788610, PubMed:20673219, PubMed:22365600, PubMed:24088714, PubMed:28939839, PubMed:37962578). … Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:20673219).

    Polypeptides: Protein O-GlcNAcaseSynonyms: Nuclear cytoplasmic O-GlcNAcase and acetyltransferase
  6. Target

    Sialate O-acetylesterase

    go.drugbank.com/bio_entities/BE0019865
    EnzymeHumans

    Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates … in the lysosomes (Probable).

    Polypeptides: Sialate O-acetylesteraseSynonyms: Sialic acid-specific 9-O-acetylesterase
  7. Drug

    Zofenopril

    go.drugbank.com/drugs/DB13166
    ApprovedInvestigational

    Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

    Mixtures: ZOFENOPRIL E IDROCLOROTIAZIDE DOC GENERICI, ZOFENOPRIL E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Nitroglycerin

    go.drugbank.com/drugs/DB00727
    ApprovedInvestigational

    [A249965] Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due to coronary artery disease,[L7102,L7141,L38369,L42320] peri-operative hypertension, congestive heart

    Mixtures: Nitroglycerin In 5% Dextrose Inj.-400mcg/ml, Nitroglycerin In 5% Dextrose Inj.-200mcg/mlCategories: Compounds used in a research, industrial, or household setting, Vasodilators Used in Cardiac Diseases
  9. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    Follitropin beta is produced in genetically engineered Chinese hamster cell lines (CHO). … Follitropin is important in the development of follicles produced by the ovaries.

    Synonyms: FSH-a, FSH-bInternational brands: Cinnal-F
  10. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Synonyms: (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: PIPERACILLINA E TAZOBACTAM MYLAN GENERICS, PIPERACILLINA E TAZOBACTAM MYLAN GENERICS