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Displaying results 551 - 560 of 10000 in total
  1. Drug

    Mertiatide

    go.drugbank.com/drugs/DB15780
    Investigational

    Products: Mertioscan 0,2 mg Kit für ein radioaktives Arzneimittel
  2. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate … Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the

    Products: IVABRADINA EG
  3. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutaseSynonyms: Superoxide dismutase copper chaperone
  4. Target

    Cytochrome c oxidase copper chaperone

    go.drugbank.com/bio_entities/BE0008686
    CarrierHumans

    Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV) (PubMed:15229189, PubMed:19393246, PubMed:31903891, PubMed:35750769). … Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone

    Polypeptides: Cytochrome c oxidase copper chaperoneFunction: copper chaperone activity
  5. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [L32283] In addition, oral ketotifen is used in Mexico and across Europe for the treatment of various allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. … available and indicated as an add-on therapy for children with atopic asthma.

    Products: KETOTIFENE EG, Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen
  6. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.

    Mixtures: DORZOLAMID AL COMP ATR, DORZOLAMID AL COMP ATRProducts: Timolol Maleate-EX, Timoptic in Ocudose
  7. Indication

    Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex

    go.drugbank.com/conditions/DBCOND0159090
    Drugs: Durlobactam · Sulbactam
    Synonyms: Nosocomial Pneumonia caused by Acinetobacter Baumannii-calcoaceticus Complex
  8. Drug

    Carbamide peroxide

    go.drugbank.com/drugs/DB11129
    ApprovedInvestigational

    of this ingredient as an oral wound healing agent [L1976]. … The FDA considers carbamide peroxide to be safe in oral mucosal injury drug products as an oral wound healing agent, although there is insufficient data to establish general recognition of the effectiveness

    Categories: Compounds used in a research, industrial, or household settingInternational brands: Sential E
  9. Target

    Amine oxidase [copper-containing] 3

    go.drugbank.com/bio_entities/BE0001002
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:19588076, PubMed:24304424, PubMed:9653080). Has a preference for the primary mo...

    Polypeptides: Amine oxidase [copper-containing] 3Synonyms: Copper amine oxidase, Amine oxidase copper-containing 3
  10. Target

    Polycomb complex protein BMI-1

    go.drugbank.com/bio_entities/BE0013109
    TargetHumans

    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development … In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:21772249, PubMed:26151332)

    Polypeptides: Polycomb complex protein BMI-1