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Displaying results 5601 - 5610 of 10000 in total
  1. Target

    MAP kinase-activated protein kinase 5

    go.drugbank.com/bio_entities/BE0009478
    TargetHumans

    Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2

    Polypeptides: MAP kinase-activated protein kinase 5Synonyms: MK-5, MAPKAPK-5
  2. Target

    Solute carrier family 12 member 5

    go.drugbank.com/bio_entities/BE0009674
    TransporterMouse

    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (By similarity). As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required f...

    Polypeptides: Solute carrier family 12 member 5Synonyms: K-Cl cotransporter 2, Electroneutral potassium-chloride cotransporter 2
  3. Target

    Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

    go.drugbank.com/bio_entities/BE0010803
    TargetHumans

    Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating … Also, is able to hydrolyze the 5-phosphate of phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P3), 1D-myo-inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate (PubMed:10764818, PubMed:

    Polypeptides: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1Synonyms: Inositol polyphosphate-5-phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa
  4. Target

    C-X-C motif chemokine 5

    go.drugbank.com/bio_entities/BE0010821
    TargetHumans

    Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes

    Polypeptides: C-X-C motif chemokine 5
  5. Target

    1-phosphatidylinositol 3-phosphate 5-kinase

    go.drugbank.com/bio_entities/BE0021269
    TargetHumans

    Also catalyzes the phosphorylation of phosphatidylinositol on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:22621786). … Autophosphorylation inhibits its own phosphatidylinositol 3-phosphate 5-kinase activity, stimulates FIG4 lipid phosphatase activity and down-regulates lipid product formation (PubMed:33098764).

    Polypeptides: 1-phosphatidylinositol 3-phosphate 5-kinaseSynonyms: Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type III
  6. Drug

    Raludotatug deruxtecan

    go.drugbank.com/drugs/DB19447
    Investigational

    Raludotatug deruxtecan is under investigation in clinical trial NCT06660654 (A Study of Raludotatug Deruxtecan in Participants With Advanced/metastatic Solid Tumors (Rejoice-pantumor01)).

    Synonyms: immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody conjugated to deruxtecan, comprising a linker and a camptothecin, 220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (3
  7. Drug

    Protokylol

    go.drugbank.com/drugs/DB06814
    ApprovedVet approved

    Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.

    Categories: Adrenergic beta-2 Receptor Agonists, Heterocyclic Compounds, 1-RingProducts: OPTİCAİNE %0.5 GÖZ DAMLASI, ÇÖZELTİ 5 ML
  8. Drug

    Potassium Iodide

    go.drugbank.com/drugs/DB06715
    ApprovedInvestigational

    SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

    Mixtures: I D M Expectorant Tab, Folika-MGProducts: YODOFAM JARABE X 120 ML, Kaliumiodid SERB 65 mg Tabletten
  9. Target

    Bcl-2-like protein 2

    go.drugbank.com/bio_entities/BE0003420
    TargetHumans

    Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX

    Polypeptides: Bcl-2-like protein 2Synonyms: Bcl2-L-2
  10. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … Human insulin is also available in an inhalable form, intended to be used as a bolus meal-time insulin.

    Mixtures: MIXTARD 30 HM PENFİLL 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN KARTUŞ, 5 ADET, MIXTARD 30 HM PENFİLL 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN KARTUŞ, 5 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers