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Displaying results 5641 - 5650 of 10000 in total
  1. Target

    Galectin-2

    go.drugbank.com/bio_entities/BE0003247
    TargetHumans

    This protein binds beta-galactoside. Its physiological function is not yet known

    Polypeptides: Galectin-2Synonyms: Gal-2, S-Lac lectin 2
  2. Target

    Acylphosphatase-2

    go.drugbank.com/bio_entities/BE0004569
    TargetHumans

    catalyzes the hydrolysis of acylphosphates compounds containing a carboxylphosphate bond

    Polypeptides: Acylphosphatase-2Synonyms: Acylphosphate phosphohydrolase 2
  3. Target

    Prohibitin-2

    go.drugbank.com/bio_entities/BE0009007
    TargetHumans

    Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...

    Polypeptides: Prohibitin-2
  4. Target

    Angiopoietin-2

    go.drugbank.com/bio_entities/BE0010028
    TargetHumans

    Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (PubM...

    Polypeptides: Angiopoietin-2Synonyms: ANG-2
  5. Target

    Neuropilin-2

    go.drugbank.com/bio_entities/BE0010030
    TargetHumans

    High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF

    Polypeptides: Neuropilin-2Synonyms: Vascular endothelial cell growth factor 165 receptor 2
  6. Target

    Presenilin-2

    go.drugbank.com/bio_entities/BE0011014
    TargetHumans

    Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10497236, PubMed:1...

    Polypeptides: Presenilin-2Synonyms: PS-2, STM-2
  7. Target

    Kallikrein-2

    go.drugbank.com/bio_entities/BE0012874
    TargetHumans

    Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin

    Polypeptides: Kallikrein-2Synonyms: Tissue kallikrein-2
  8. Target

    Frizzled-2

    go.drugbank.com/bio_entities/BE0014542
    TargetHumans

    Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and...

    Polypeptides: Frizzled-2Synonyms: Fz-2
  9. Drug

    Pentazocine

    go.drugbank.com/drugs/DB00652
    ApprovedVet approved

    The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor.

    Categories: P-glycoprotein substratesProducts: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/ml
  10. Drug

    XPro1595

    go.drugbank.com/drugs/DB16454
    Investigational

    XPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.

    Synonyms: HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA., -METHOXYPOLY(OXYETHANE-1,2-DIYL))PROPYL)CARBAMOYL)ETHYL)-2,5-DIOXOPYRROLIDIN-3-YL)-L-CYSTEINYL