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Presenilin-2
go.drugbank.com/bio_entities/BE0011014TargetHumansCatalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10497236, PubMed:1...
Polypeptides: Presenilin-2Synonyms: PS-2, STM-2Kallikrein-2
go.drugbank.com/bio_entities/BE0012874TargetHumansGlandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin
Polypeptides: Kallikrein-2Synonyms: Tissue kallikrein-2Frizzled-2
go.drugbank.com/bio_entities/BE0014542TargetHumansReceptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and...
Polypeptides: Frizzled-2Synonyms: Fz-2Evening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceutical[A33131] Evening primrose oil has been filled for the FDA by Humanetics Corporation on April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of safety". … Evening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used as an alternative source for omega-6 essential fatty acids.
Mixtures: OGAMIX(Evening primrose oil 500 mg, Lecithin oil 500 mg, Fish oil 125 mgand Vitamin E 10 mg Soft Gelatin Capsule), PRIM E CAPSULECategories: Fatty Acids, Omega-6, Cytochrome P-450 CYP2C19 InhibitorsAcylcarnitine 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine
smpdb.ca/view/SMP0123510Metabolic5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoyl-CoA reacts with L-carnitine to form 5-(3,4-dimethyl-5-pentylfuran-2-yl)pentanoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrialLevodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLProducts: İSODOS 60 MG/5 ML ŞURUP, 1 ADET, DROPOLEV-S 30 MG/5 ML ŞURUPPentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedThe first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor.
Categories: P-glycoprotein substratesProducts: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlAcylcarnitine 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine
smpdb.ca/view/SMP0123511Metabolic5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-(3-methyl-5-pentylfuran-2-yl)pentanoyl-CoA reacts with L-carnitine to form 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrialInterleukin-2
go.drugbank.com/bio_entities/BE0001029TargetHumansCytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance (PubMed:6438535). Binds to a rec...
Polypeptides: Interleukin-2Synonyms: IL-2Carboxylesterase 2
go.drugbank.com/bio_entities/BE0003048TargetPseudomonas fluorescensHydrolyzes carboxylic ester bonds with relatively broad substrate specificity.
Polypeptides: Carboxylesterase 2