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Conjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalHowever, until 1986 official clinical trials were performed and this product was determined to be effective for the treatment of osteoporosis. … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.
Categories: Sex Hormones and Modulators of the Genital SystemMepenzolate
go.drugbank.com/drugs/DB04843ApprovedWithdrawnIt has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications. … Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor.
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnAll of the derivatives have slight different physicochemical properties when compared to the parent structure. … [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]
Diethylpropion
go.drugbank.com/drugs/DB00937ApprovedIllicitInvestigationalIt is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290) … A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMebanazine
go.drugbank.com/drugs/DB09248ApprovedWithdrawnMebanazine, also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of chemicals. … It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSpirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalSpirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Agents Acting on the Renin-Angiotensin SystemAlanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalIt is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Mixtures: Clinimix E, Clinimix EFerrous bisglycinate
go.drugbank.com/drugs/DB11210ApprovedIt is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.
Mixtures: healthy mamaBE WELL ROUNDED BE WELL ROUNDED, VINATAL DHA CAPSULA DE GELATINA BLANDANystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approved[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly … [A188562] As it undergoes very little absorption following oral or topical administration, nystatin's efficacy is limited to the treatment/prevention of cutaneous, mucocutaneous, and gastrointestinal fungal
Mixtures: GYNECON - T, NISTATINA + OXIDO DE ZINCTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigationalTenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [A178060] Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal
Categories: Antivirals used in combination for the treatment of HIV infections