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Displaying results 571 - 580 of 10000 in total
  1. Target

    S-adenosylmethionine decarboxylase proenzyme

    go.drugbank.com/bio_entities/BE0000101
    TargetHumans

    Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels

    Polypeptides: S-adenosylmethionine decarboxylase proenzyme
  2. Target

    (S)-2-haloacid dehalogenase

    go.drugbank.com/bio_entities/BE0001647
    TargetPseudomonas sp. (strain YL)

    Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids (PubMed:7490277, PubMed:9614112). … Active with 2-halogenated carboxylic acids and converts only the S-isomer (or L-isomer) of 2-chloropropionic acid with inversion of configuration to produce R-lactate (or D-isomer) (PubMed:7490277, PubMed

    Polypeptides: (S)-2-haloacid dehalogenaseFunction: (S)-2-haloacid dehalogenase activity
  3. Target

    Glutathione S-transferase GstA

    go.drugbank.com/bio_entities/BE0002062
    TargetEscherichia coli (strain K12)

    Catalyzes the conjugation of reduced glutathione (GSH) to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and ethacrynic acid. Also possesses thiol:disulfide o...

    Polypeptides: Glutathione S-transferase GstA
  4. Target

    Glutathione S-transferase A1

    go.drugbank.com/bio_entities/BE0002281
    TargetEnzymeHumans

    Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).

    Polypeptides: Glutathione S-transferase A1
  5. Target

    Glutathione S-transferases (Cytosolic)

    go.drugbank.com/bio_entities/BE0010006
    TargetEnzymeHumans

    Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator … Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable).

    Polypeptides: Glutathione S-transferase A1, Glutathione S-transferase A2Synonyms: Glutathione S-transferase, Glutathione S-transferase theta-2
  6. Drug

    Pentetic acid

    go.drugbank.com/drugs/DB14007
    ApprovedInvestigational

    [A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA. … [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004.[L1469]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: DTP-A
  7. Drug

    Omidenepag isopropyl

    go.drugbank.com/drugs/DB15071
    Approved

    [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the first-line therapy for ocular hypertension and primary open-angle glaucoma; however, not all patients … The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. Omidenepag IOP-lowering effect is comparable to the one observed with [latanoprost].

    Categories: Receptors, Prostaglandin E, EP2 Subtype, agonists, Heterocyclic Compounds, 1-RingSynonyms: isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinate
  8. Drug

    Fenofibrate

    go.drugbank.com/drugs/DB01039
    ApprovedInvestigational

    Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.

    Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateMixtures: SIMITRI®145/20MG, PRAVAFEN® CAPSULAS
  9. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Synonyms: Monoctanoin component DMixtures: Mycellcare iT s, MINICA S ENEMA
  10. Drug

    Didecyldimethylammonium

    go.drugbank.com/drugs/DB04221
    ApprovedInvestigational

    Mixtures: VIR-U-CLEAN Disinfectant Cleaning Wipes, Pure Formula 1 advanced wipes 50wipes 01Products: S D S