Search

Displaying results 5841 - 5850 of 10000 in total
  1. Target

    Retinal dehydrogenase 2

    go.drugbank.com/bio_entities/BE0000513
    TargetHumans

    Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (...

    Polypeptides: Retinal dehydrogenase 2Synonyms: RALDH 2, Retinaldehyde-specific dehydrogenase type 2
  2. Target

    Glutamate carboxypeptidase 2

    go.drugbank.com/bio_entities/BE0000568
    TargetHumans

    Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory n...

    Polypeptides: Glutamate carboxypeptidase 2
  3. Target

    Heme oxygenase 2

    go.drugbank.com/bio_entities/BE0000587
    TargetHumans

    Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron

    Polypeptides: Heme oxygenase 2Synonyms: HO-2
  4. Target

    Glutamate decarboxylase 2

    go.drugbank.com/bio_entities/BE0000602
    TargetHumans

    Catalyzes the production of GABA

    Polypeptides: Glutamate decarboxylase 2
  5. Target

    Serine palmitoyltransferase 2

    go.drugbank.com/bio_entities/BE0000660
    TargetHumans

    Component of the serine palmitoyltransferase multisubunit enzyme (SPT) that catalyzes the initial and rate-limiting step in sphingolipid biosynthesis by condensing L-serine and activated acyl-CoA (most commonly palmitoyl-CoA) to form lon...

    Polypeptides: Serine palmitoyltransferase 2Synonyms: LCB 2, SPT 2
  6. Target

    Glutamate receptor 2

    go.drugbank.com/bio_entities/BE0000829
    TargetHumans

    Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic

    Polypeptides: Glutamate receptor 2Synonyms: GluR-2, AMPA-selective glutamate receptor 2
  7. Target

    Thiamine transporter 2

    go.drugbank.com/bio_entities/BE0000963
    TransporterHumans

    Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism (PubMed:11731220, PubMed:33008889, PubMed:35512554, PubMed:35724964). Has no folate transport activity (PubMed:11731220). Mediates H(+)-dependent pyridoxin...

    Polypeptides: Thiamine transporter 2Synonyms: ThTr-2
  8. Target

    Integrin beta-2

    go.drugbank.com/bio_entities/BE0001041
    TargetHumans

    Integrin ITGAL:ITGB2 is a receptor for ICAM1, ICAM2 and ICAM3 (PubMed:1676048, PubMed:23775590, PubMed:38195629). Integrin ITGAL:ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated ...

    Polypeptides: Integrin beta-2
  9. Target

    Alpha-2-antiplasmin

    go.drugbank.com/bio_entities/BE0001125
    TargetHumans

    Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin

    Polypeptides: Alpha-2-antiplasminSynonyms: Alpha-2-AP, Alpha-2-PI
  10. Target

    L-asparaginase 2

    go.drugbank.com/bio_entities/BE0001351
    TargetEscherichia coli (strain K12)

    Polypeptides: L-asparaginase 2