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Displaying results 5861 - 5870 of 10000 in total
  1. Target

    Beta-arrestin-2

    go.drugbank.com/bio_entities/BE0013128
    TargetHumans

    AP-2) in clathrin-coated pits (CCPs). … Increases ERK1/2 signaling in AGTR1- and AVPR2-mediated activation (reciprocal regulation). Involved in CCR7-mediated ERK1/2 signaling involving ligand CCL19.

    Polypeptides: Beta-arrestin-2Synonyms: Arrestin beta-2
  2. Target

    Urotensin-2 receptor

    go.drugbank.com/bio_entities/BE0020904
    TargetHumans

    G protein-coupled receptor for the vasoactive neuropeptides urotensin-2 and urotensin-2B (PubMed:14550283).

    Polypeptides: Urotensin-2 receptorSynonyms: UR-2-R
  3. Target

    Beta-secretase 2

    go.drugbank.com/bio_entities/BE0021401
    TargetHumans

    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-assoc...

    Polypeptides: Beta-secretase 2Synonyms: Beta-site APP cleaving enzyme 2, Beta-site amyloid precursor protein cleaving enzyme 2
  4. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.

    Mixtures: RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK), PRO TB 2Categories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 Inducers
  5. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI

    Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates
  6. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.

    Synonyms: 1-adamantanamine, 1-adamantylamineMixtures: Innoprax-5, ROSEL-T
  7. Drug

    Iodoform

    go.drugbank.com/drugs/DB13813
    ApprovedInvestigationalVet approvedWithdrawn

    Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more primarily used for veterinary purposes. … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry.

    Products: Iodoform Packing Strip 5% W/w, Iodoform Nugauze Packing Strip 5%
  8. Pathway

    Acylcarnitine (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123550
    Metabolic

    (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine is an acylcarnitine. … membrane to once again form (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoyl-CoA and L-carnitine. (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5, Carnitine O-palmitoyltransferase 2, mitochondrial
  9. Drug

    Ferrous glycine sulfate

    go.drugbank.com/drugs/DB14501
    Approved

    Products: FERRO SANOL DUODENAL 100 MG KAPSUL, 20 ADET, FERRO SANOL DUODENAL 100 MG KAPSUL, 50 ADET
  10. Target

    5'-AMP-activated protein kinase subunit beta-1

    go.drugbank.com/bio_entities/BE0000254
    TargetHumans

    Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-pro...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1