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Naloxone Action Pathway
smpdb.ca/view/SMP0000688Drug actionIn recent study, naloxone shows that it can also bind to kappa and gamma-opioid receptors.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Benzocaine Action Pathway
smpdb.ca/view/SMP0000392Drug actionOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Mepivacaine Action Pathway
smpdb.ca/view/SMP0000399Drug actionOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Prilocaine Action Pathway
smpdb.ca/view/SMP0000401Drug actionOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Ropivacaine Action Pathway
smpdb.ca/view/SMP0000404Drug actionOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Heroin Action Pathway
smpdb.ca/view/SMP0000407Drug actionThey are beta-endorphin, dynorphin, leu-enkephalin, and met-enkephalin. … Endorphins are regularly released in the brain and nerves, attenuating pain.
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Levallorphan Action Pathway
smpdb.ca/view/SMP0000683Drug actionLevallorphan (also known as Lorfan and Naloxifan) is a type of medication that can be used for treating drug overdoses and respirotry depression. … Levallorphan can bind to mu-type opioid receptor and kappa-type opioid receptor on neuron of central nerves system (CNS).
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Buprenorphine Action Pathway
smpdb.ca/view/SMP0000684Drug actionand symptoms of withdrawal. … Buprenorphine, trade name subutex, suboxone, zubsolv and bunavail, is a partial agonist of mu-opioid receptors and a kappa-opioid receptor antagonist and is prescribed for opioid addiction to prevent cravings
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Naltrexone Action Pathway
smpdb.ca/view/SMP0000687Drug actionNaltrexone (also known as ReVia and Vivitrol) is a competitive antagonist of mu-type opioid receptor in the central nervous system (CNS).
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1Nalbuphine Action Pathway
smpdb.ca/view/SMP0000691Drug actionNalbuphine (also known as Rubuphine and Nubain) is a competitive antagonist of mu-type and kappa-type opioid receptor in the central nervous system (CNS).
Enzymes: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1