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Apomorphine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126633Drug actionApomorphine is a non-ergoline dopamine agonist with high binding affinity to dopamine D2, D3, and D5 receptors. Stimulation of D2 receptors in the caudate-putamen, a region of the brain responsible for locomotor control, may be responsib...
Epicriptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126655Drug actionEpicriptine effect is mainly due to the agonistic activity on dopamine receptor. Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dih...
Tranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126672Drug actionTranylcypromine is a non-hydrazine monoamine oxidase inhibitor belonging to the class of antidepressants called MAOIs. This drug is indicated in the treatment of major depression, dysthymic disorder, and atypical depression. It also is u...
Phenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126682Drug actionPhenelzine, also known as Nardil, is a monoamine oxidase inhibitor (MAOIs). This drug is used as an antidepressant and it is also effective in the treatment of panic disorder and social anxiety disorder. The monoamine oxidase is an enzym...
Minaprine Amine oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126684Drug actionMinaprine is an amino-phenylpyridazine antidepressant. It is indicated in the treatment of various depressive states. Minaprine acts on many targets in the neurons. Firstly, this drug binds as an antagonist to the serotonin type 2 recept...
Moclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126685Drug actionMoclobemide is a reversible monoamine oxidase inhibitor (MAOIs) selective for the isoform A (RIMA). This molecule is indicated in the treatment of major depressive disorder (MDD) and bipolar disorder. he monoamine oxidase is an enzyme th...
Pargyline Action Pathway
smpdb.ca/view/SMP0126708Drug actionPargyline is a monoamine oxidase B inhibitor (MAOIs). This drug has antihypertensive properties and is, thus, indicated in the treatment of moderate to severe hypertension. Pargyline inhibits the breakdown of monoamine neurotransmitters,...
Rasagiline Action Pathway
smpdb.ca/view/SMP0126709Drug actionRasagiline is a propargylamine and an irreversible monoamine oxidase inhibitor (MAOIs). It is indicated in the treatment of idiopathic Parkinson's disease as initial therapy or as adjunct therapy with levodopa. The monoamine oxidase is a...
Benzatropine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126985Drug actionBenzatropine, known commonly as Cogentin, is an anticholinergic drug used to treat Parkinson's disease and extrapyramidal symptoms, except tardive dyskinesia. Benzatropine is used in therapy for parkinsonism, referring to a group of neur...
Benzphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126989Drug actionBenzphetamine, commonly known as Didrex, is a sympathomimetic used to treat exogenous obesity. It has properties similar to dextroamphetamine. This drug can be used as a short-term treatment of obesity when combined with altered lifestyl...