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Displaying results 51 - 60 of 178 in total
  1. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). … Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat and immunoglobulin domain-containing protein 1
  2. Target

    Thyroxine 5-deiodinase

    go.drugbank.com/bio_entities/BE0009333
    TargetEnzymeHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722 … to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-T1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and

    Synonyms: Type 3 DI
  3. Target

    Diadenosine hexaphosphate hydrolase

    go.drugbank.com/bio_entities/BE0002822
    TargetThermus thermophilus

    Specifically hydrolyzes (di)adenosine polyphosphates but not ATP or diadenosine triphosphate, generating ATP as the product. … It also hydrolyzes diadenosine pentaphosphate (Ap5A), diadenosine tetraphosphate (Ap4A) and adenosine tetraphosphate (p4A).

    Synonyms: ATP-generating (di)nucleotide polyphosphate hydrolase
  4. Target

    Type II iodothyronine deiodinase

    go.drugbank.com/bio_entities/BE0009855
    EnzymeTargetHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:11108274, PubMed:10403186, PubMed:18821722 … Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine and 3',5'- diiodothyronamine (PubMed:18339710)

    Synonyms: Type 2 DI
  5. Target

    Type I iodothyronine deiodinase

    go.drugbank.com/bio_entities/BE0009854
    EnzymeTargetHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:32718224, PubMed:18821722). … Catalyzes the deiodination of L-thyroxine sulfate and 3,3',5-triiodo-L-thyronine sulfate via IRD and of 3,3',5'-triiodo-L-thyronine sulfate via ORD (By similarity)

    Synonyms: Type 1 DI
  6. Target

    Glycerol kinase

    go.drugbank.com/bio_entities/BE0001609
    TargetEscherichia coli (strain K12)

    Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. … It also catalyzes the phosphorylation of dihydroxyacetone, L-glyceraldehyde and D-glyceraldehyde. It uses only ATP.

    Polypeptides: Glycerol kinase
  7. Target

    Glycerol dehydratase

    go.drugbank.com/bio_entities/BE0002565
    TargetClostridium butyricum

    Polypeptides: Glycerol dehydrataseSynonyms: Glycerol dehydratase, B12-independent glycerol dehydratase
  8. Target

    Band 3 anion transport protein

    go.drugbank.com/bio_entities/BE0012390
    TransporterTargetHumans

    Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic … domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin (PubMed:1538405, PubMed:20151848, PubMed:35835865).

    Synonyms: DI
  9. Target

    Glycosyl transferase

    go.drugbank.com/bio_entities/BE0002699
    TargetNeisseria meningitidis

    Polypeptides: Glycosyl transferase
  10. Target

    Glycerol uptake facilitator protein

    go.drugbank.com/bio_entities/BE0002037
    TransporterEscherichia coli (strain K12)

    the trivalent inorganic forms of arsenic and antimony (PubMed:14970228, PubMed:6998951, PubMed:9150238). … may also have limited permeability to various other substrates, including xylitol, erythritol, D-arabitol, L-arabitol, ribitol, D-galactitol, D-mannitol, D-sorbitol, urea, glycine, D/L-glyceraldehyde and

    Polypeptides: Glycerol uptake facilitator proteinSynonyms: Glycerol facilitator