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Displaying results 51 - 60 of 100 in total
  1. Target

    Fluorinase

    go.drugbank.com/bio_entities/BE0003167
    TargetStreptomyces cattleya

    Catalyzes the formation of a C-F bond by combining S-adenosyl-L-methionine (SAM) and fluoride to generate 5'-fluoro-5'-deoxyadenosine (5'-FDA) and L-methionine.

  2. Target

    Hydroxymycolate synthase MmaA4

    go.drugbank.com/bio_entities/BE0003863
    TargetMycobacterium tuberculosis

    Involved in the biosynthesis of hydroxymycolate, a common precursor of oxygenated mycolic acids (methoxy-mycolate and keto-mycolate). Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or sim...

  3. Target

    Peptide deformylase 1

    go.drugbank.com/bio_entities/BE0003874
    TargetBacillus cereus (strain ATCC 14579 / DSM 31)

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

  4. Target

    Peptide deformylase 2

    go.drugbank.com/bio_entities/BE0003875
    TargetBacillus cereus (strain ATCC 14579 / DSM 31)

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

  5. Target

    Peptide deformylase

    go.drugbank.com/bio_entities/BE0004391
    TargetHelicobacter pylori

    N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

  6. Target

    Diphthine methyl ester synthase

    go.drugbank.com/bio_entities/BE0004441
    TargetHumans

    S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine

  7. Target

    Lanosterol synthase

    go.drugbank.com/bio_entities/BE0004668
    TargetYeast

    Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

  8. Target

    Sodium-coupled neutral amino acid transporters

    go.drugbank.com/bio_entities/BE0009976
    TargetHumans

    Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine (PubMed

  9. Target

    Translation initiation factor eIF2B subunit epsilon

    go.drugbank.com/bio_entities/BE0014384
    TargetHumans

    Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available

  10. Target

    Translation initiation factor eIF2B subunit alpha

    go.drugbank.com/bio_entities/BE0014461
    TargetHumans

    Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available