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Displaying results 51 - 60 of 72 in total
  1. Target

    UDP-glucuronosyltransferase 2B15

    go.drugbank.com/bio_entities/BE0004696
    EnzymeHumans

    Catalyzes the glucuronidation of monoterpenoid alcohols such as borneol, menthol and isomenthol, a class of natural compounds used in essential oils (By similarity)

  2. Target

    Peroxiredoxin-1

    go.drugbank.com/bio_entities/BE0005844
    TargetEnzymeHumans

    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

  3. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Involved in the incentive salience of drugs: controls responses to drug-related stimuli, making it a key target for reducing addiction to substances like cocaine, morphine, and alcohol (PubMed:10432116

  4. Target

    Protein kinase C gamma type

    go.drugbank.com/bio_entities/BE0009588
    TargetHumans

    neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol

  5. Target

    Human Cyclooxygenases

    go.drugbank.com/bio_entities/BE0010085
    TargetHumans

    Oxygenates PUFAs to hydroperoxy compounds and then reduces them to corresponding alcohols (PubMed:11034610, PubMed:11192938, PubMed:9048568, PubMed:9261177).

  6. Target

    Human Carboxylesterases

    go.drugbank.com/bio_entities/BE0010086
    EnzymeTargetHumans

    Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol (PubMed:28677105).

  7. Target

    Dehydrogenase/reductase SDR family member 9

    go.drugbank.com/bio_entities/BE0018870
    EnzymeHumans

    3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (PubMed:11294878, PubMed:29541409). Also plays a role in th...

    Function: alcohol dehydrogenase (NAD+) activity
  8. Target

    Haloalkane dehalogenase

    go.drugbank.com/bio_entities/BE0027482
    TargetEnzymeSphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S)

    Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. … Has a broad substrate specificity since not only monochloroalkanes (C3 to C10) but also dichloroalkanes (> C3), bromoalkanes, and chlorinated aliphatic alcohols are good substrates (PubMed:10100638, PubMed

  9. Target

    Prostaglandin G/H synthase 2

    go.drugbank.com/bio_entities/BE0000262
    TargetEnzymeHumans

    Oxygenates PUFAs to hydroperoxy compounds and then reduces them to corresponding alcohols (PubMed:11034610, PubMed:11192938, PubMed:9048568, PubMed:9261177).

  10. Target

    Sterol 26-hydroxylase, mitochondrial

    go.drugbank.com/bio_entities/BE0000549
    EnzymeHumans

    Hydroxylates (with R stereochemistry) the terminal methyl group of cholesterol side-chain in a three step reaction to yield at first a C26 alcohol, then a C26 aldehyde and finally a C26 acid (PubMed:12077124