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Parathyroid hormone 2 receptor
go.drugbank.com/bio_entities/BE0004703TargetHumansThis is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a si...
Polypeptides: Parathyroid hormone 2 receptorEquilibrative nucleoside transporter 2
go.drugbank.com/bio_entities/BE0004706TransporterTargetHumansBidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed:10722669, PubMed:12527552, PubMed:12590919, PubMed:16214850, PubMed:21795683...
Polypeptides: Equilibrative nucleoside transporter 2Synonyms: Solute carrier family 29 member 2Sodium/glucose cotransporter 2
go.drugbank.com/bio_entities/BE0004753TargetTransporterHumansElectrogenic Na(+)-coupled sugar symporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1 (PubMed:20980548, PubMed:28592437, PubMed:34880493, PubMed:37217492, PubMed:38057552). Tran...
Polypeptides: Sodium/glucose cotransporter 2Synonyms: Solute carrier family 5 member 2, Na(+)/glucose cotransporter 2Sodium/nucleoside cotransporter 2
go.drugbank.com/bio_entities/BE0004781TransporterHumansSodium-dependent and purine-selective transporter (PubMed:10087507, PubMed:9435697). Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine) (Pub...
Polypeptides: Sodium/nucleoside cotransporter 2Synonyms: CNT 2, Na(+)/nucleoside cotransporter 2Mitochondrial 2-oxodicarboxylate carrier
go.drugbank.com/bio_entities/BE0008678TransporterHumansCan transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate ( … 2-aminohexanedioate), oxaloacetate, and citrate (PubMed:11083877).
Polypeptides: Mitochondrial 2-oxodicarboxylate carrierSynonyms: Mitochondrial 2-oxoadipate carrierGrowth/differentiation factor 2
go.drugbank.com/bio_entities/BE0010630TargetHumansPotent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG
Polypeptides: Growth/differentiation factor 2Synonyms: GDF-2Bromodomain-containing protein 2
go.drugbank.com/bio_entities/BE0012869TargetHumansSpecifically binds histone H4 acetyl-methylated at 'Lys-5' and 'Lys-12' (H4K5acme and H4K12acme, respectively) (PubMed:37731000) … Chromatin reader protein that specifically recognizes and binds histone H4 acetylated at 'Lys-5' and 'Lys-12' (H4K5ac and H4K12ac, respectively), thereby controlling gene expression and remodeling chromatin
Polypeptides: Bromodomain-containing protein 2Extracellular sulfatase Sulf-2
go.drugbank.com/bio_entities/BE0016611TargetHumansExhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:30788513, PubMed:35294879). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact...
Polypeptides: Extracellular sulfatase Sulf-2Synonyms: hSulf-2Nicotinamide riboside kinase 2
go.drugbank.com/bio_entities/BE0019876TargetHumansCatalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to lami...
Polypeptides: Nicotinamide riboside kinase 2Synonyms: NRK 2, RNK 2LanC-like protein 2
go.drugbank.com/bio_entities/BE0020245TargetHumansNecessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes
Polypeptides: LanC-like protein 2