Search

Displaying results 641 - 650 of 1186 in total
  1. Target

    Glutamate receptor ionotropic, kainate 3

    go.drugbank.com/bio_entities/BE0000832
    TargetHumans

    The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:7719709). … Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.

    Polypeptides: Glutamate receptor ionotropic, kainate 3Synonyms: Glutamate receptor 7, Excitatory amino acid receptor 5
  2. Target

    Glucagon-like peptide 1 receptor

    go.drugbank.com/bio_entities/BE0000857
    TargetHumans

    G protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449, PubMed:7517895, PubMed:8216285, PubMed:8405712).

    Polypeptides: Glucagon-like peptide 1 receptorSynonyms: GLP-1 receptor
  3. Target

    Receptor activity-modifying protein 3

    go.drugbank.com/bio_entities/BE0000861
    TargetHumans

    estrogen receptor 1 (GPER1) (PubMed:23674134, PubMed:9620797). … Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 (PubMed:32296767). Together with CALCR, act as a receptor complex for amylin/IAPP (PubMed:35324283)

    Polypeptides: Receptor activity-modifying protein 3Synonyms: Calcitonin-receptor-like receptor activity-modifying protein 3
  4. Target

    TGF-beta receptor type-2

    go.drugbank.com/bio_entities/BE0001861
    TargetHumans

    Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. … Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4.

    Polypeptides: TGF-beta receptor type-2Synonyms: TGF-beta receptor type II, TGF-beta type II receptor
  5. Target

    Glucagon-like peptide 2 receptor

    go.drugbank.com/bio_entities/BE0002134
    TargetHumans

    This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

    Polypeptides: Glucagon-like peptide 2 receptorSynonyms: GLP-2 receptor
  6. Target

    Neuropeptide Y receptor type 4

    go.drugbank.com/bio_entities/BE0002418
    TargetHumans

    G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP (PubMed:7493937, PubMed:7592911).

    Polypeptides: Neuropeptide Y receptor type 4Synonyms: Pancreatic polypeptide receptor 1
  7. Target

    Neuropeptide Y receptor type 1

    go.drugbank.com/bio_entities/BE0002451
    TargetHumans

    Receptor for neuropeptide Y (NPY) and peptide YY (PYY) (PubMed:1317848, PubMed:1321422, PubMed:35165283, PubMed:35507650, PubMed:38882210). … As a receptor for NPY, it is involved in the regulation of eating behavior and NPY-induced stimulation of food intake (By similarity).

    Polypeptides: Neuropeptide Y receptor type 1Function: neuropeptide receptor activity
  8. Target

    GM-CSF receptor alpha subunit

    go.drugbank.com/bio_entities/BE0002482
    TargetHumans

    Polypeptides: GM-CSF receptor alpha subunit
  9. Target

    Type-2 angiotensin II receptor

    go.drugbank.com/bio_entities/BE0003426
    TargetHumans

    Receptor for angiotensin II, a vasoconstricting peptide (PubMed:28379944, PubMed:29967536, PubMed:31899086, PubMed:8185599).

    Polypeptides: Type-2 angiotensin II receptorSynonyms: AT2 receptor, Angiotensin II type-2 receptor
  10. Target

    Ephrin type-A receptor 5

    go.drugbank.com/bio_entities/BE0005587
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. … The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

    Polypeptides: Ephrin type-A receptor 5